Asymmetric kinetic resolution of sulfides for the construction of unsymmetric sulfides and chiral 3,3-disubstituted oxindoles

被引：8
|
作者：
Wang, Kaiye [1 ]
Xiang, Yanan [1 ]
Shi, Zhujun [1 ]
Wang, Hongyu [1 ]
Li, Na [1 ]
Tang, Bo [1 ]
机构：
[1] Shandong Normal Univ, Inst Mol & Nano Sci, Collaborat Innovat Ctr Functionalized Probes Chem, Minist Educ,Key Lab Mol & Nano Probes,Coll Chem C, Jinan 250014, Shandong, Peoples R China
来源：
ORGANIC & BIOMOLECULAR CHEMISTRY | 2019年 / 17卷 / 26期
基金：
中国国家自然科学基金; 中国博士后科学基金;
关键词：
ONE-POT SYNTHESIS; 1,6-CONJUGATE ADDITION; EFFICIENT SYNTHESIS; DISULFIDE; SULFENYLATION; OXIDATION; THIOLS;
D O I：
10.1039/c9ob01065c
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
A range of 3,3-disubstituted oxindoles accessed using para-quinone methides derived from isatins with thiols were used for the formation of unsymmetrical disulfides, and 3,3-disubstituted oxindoles with a chiral quaternary carbon center and unsymmetric disulfides could also be directly obtained with high selectivities catalyzed by chiral phosphines in one step.
引用
收藏
页码：6351 / 6354
页数：4
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