A boronate-based fluorescent probe for the selective detection of cellular peroxynitrite

被引：106
|
作者：
Kim, Jiyoung [1 ]
Park, Jeesook [1 ]
Lee, Hawon [2 ]
Choi, Yongdoo [2 ]
Kim, Youngmi [1 ]
机构：
[1] Dankook Univ, Inst Nanosensor & Biotechnol, Dept Chem, Yongin 448701, Gyeonggi Do, South Korea
[2] Natl Canc Ctr, Mol Imaging & Therapy Branch, Goyang Si 410769, Gyeonggi Do, South Korea
来源：
CHEMICAL COMMUNICATIONS | 2014年 / 50卷 / 66期
基金：
新加坡国家研究基金会;
关键词：
NITRIC-OXIDE; OXIDATION;
D O I：
10.1039/c4cc02943g
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
A boronate-based fluorescent probe 1 for the selective monitoring of intracellular peroxynitrite has been developed. The probe takes advantage of the fast reaction of an arylboronate group with peroxynitrite, yielding a corresponding phenol that undergoes spontaneous subsequent reactions to produce a strongly fluorescent product associated with a large turn-on signal.
引用
收藏
页码：9353 / 9356
页数：4
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