Naturalistic study of the use of transcranial magnetic stimulation in the treatment of depressive relapse

被引：6
作者：
Fitzgerald, Paul B.
Benitez, Jessica
de Castella, Anthony R.
Brown, Timothy L.
Daskalakis, Z. Jeff
Kulkarni, Jayashri
机构：
[1] Monash Univ, Alfred Psychiat Res Ctr, Dept Psychol Med, Melbourne, Vic 3004, Australia
[2] Ctr Addict & Mental Hlth, Clarke Div, Toronto, ON, Canada
来源：
AUSTRALIAN AND NEW ZEALAND JOURNAL OF PSYCHIATRY | 2006年 / 40卷 / 09期
基金：
英国医学研究理事会;
关键词：
depression; relapse; transcranial magnetic stimulation;
D O I：
10.1111/j.1440-1614.2006.01881.x
中图分类号：
R749 [精神病学];
学科分类号：
100205 ;
摘要：
Background: The efficacy of repetitive transcranial magnetic stimulation (rTMS) in the treatment of depression has been assessed in a number of acute treatment trials during the last 10 years. Little is known about the long-term impact of the treatment on the disorder and its effectiveness when applied for repeated relapses of depression over time. Method: Nineteen patients who had previously responded to rTMS in clinical trials received treatment with rTMS for a total of 30 episodes of depressive relapse. Results: Approximately 10 months elapsed between treatment episodes. The majority of patients achieved a significant improvement in each treatment course with significant improvements achieved in patients treated with both low-frequency right-sided rTMS and high-frequency left-sided rTMS. Conclusions: The study suggests that rTMS may have value in the treatment of episodes of depressive relapse with little reduction in efficacy over time.
引用
收藏
页码：764 / 768
页数：5
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