Histone Lysine Demethylases and Their Functions in Plants

被引:44
作者
Luo, Ming [1 ]
Hung, Fu-Yu [2 ]
Yang, Songguang [1 ]
Liu, Xuncheng [1 ]
Wu, Keqiang [2 ]
机构
[1] Chinese Acad Sci, South China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China
[2] Natl Taiwan Univ, Coll Life Sci, Inst Plant Biol, Taipei 106, Taiwan
基金
中国国家自然科学基金;
关键词
Epigenetics; Histonedemethylase; Methylation; Chromatin; JmjC; FLOWERING-LOCUS-C; DNA METHYLATION; JMJC DOMAIN; ARABIDOPSIS-THALIANA; MONOAMINE-OXIDASE; FLORAL TRANSITION; H3K4; DEMETHYLASE; PROTEIN; CHROMATIN; EXPRESSION;
D O I
10.1007/s11105-013-0673-1
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Histone methylation-transfer of methyl groups to lysines or arginines residues of histone tails-plays an important role in the regulation of gene expression in eukaryotic cells. Histone methylation levels are regulated by histone methyltransferases and histone demethylases. There are two types of histone lysine demethylases (KDMs) in eukaryotes: KDM1/LSD1-like and JmjC domain-containing demethylases. KDMs can regulate gene expression directly through histone modification or indirectly through DNA methylation and siRNA regeneration. Recent studies indicate that KDMs play important regulatory roles in plant growth and developmental processes such as flowering time control, hormone response and circadian regulation.
引用
收藏
页码:558 / 565
页数:8
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