Histone Lysine Demethylases and Their Functions in Plants

被引:44
作者
Luo, Ming [1 ]
Hung, Fu-Yu [2 ]
Yang, Songguang [1 ]
Liu, Xuncheng [1 ]
Wu, Keqiang [2 ]
机构
[1] Chinese Acad Sci, South China Bot Garden, Key Lab Plant Resources Conservat & Sustainable U, Guangzhou 510650, Guangdong, Peoples R China
[2] Natl Taiwan Univ, Coll Life Sci, Inst Plant Biol, Taipei 106, Taiwan
基金
中国国家自然科学基金;
关键词
Epigenetics; Histonedemethylase; Methylation; Chromatin; JmjC; FLOWERING-LOCUS-C; DNA METHYLATION; JMJC DOMAIN; ARABIDOPSIS-THALIANA; MONOAMINE-OXIDASE; FLORAL TRANSITION; H3K4; DEMETHYLASE; PROTEIN; CHROMATIN; EXPRESSION;
D O I
10.1007/s11105-013-0673-1
中图分类号
Q5 [生物化学];
学科分类号
071010 ; 081704 ;
摘要
Histone methylation-transfer of methyl groups to lysines or arginines residues of histone tails-plays an important role in the regulation of gene expression in eukaryotic cells. Histone methylation levels are regulated by histone methyltransferases and histone demethylases. There are two types of histone lysine demethylases (KDMs) in eukaryotes: KDM1/LSD1-like and JmjC domain-containing demethylases. KDMs can regulate gene expression directly through histone modification or indirectly through DNA methylation and siRNA regeneration. Recent studies indicate that KDMs play important regulatory roles in plant growth and developmental processes such as flowering time control, hormone response and circadian regulation.
引用
收藏
页码:558 / 565
页数:8
相关论文
共 50 条
  • [1] Histone Lysine Demethylases and Their Functions in Plants
    Ming Luo
    Fu-Yu Hung
    Songguang Yang
    Xuncheng Liu
    Keqiang Wu
    Plant Molecular Biology Reporter, 2014, 32 : 558 - 565
  • [2] Histone lysine demethylases in Drosophila melanogaster
    Holowatyj, Andreana
    Yang, Zeng-Quan
    Pile, Lori A.
    FLY, 2015, 9 (01) : 36 - 44
  • [3] Histone lysine demethylases and their functions in cancer
    Sterling, Jayden
    Menezes, Sharleen V.
    Abbassi, Ramzi H.
    Munoz, Lenka
    INTERNATIONAL JOURNAL OF CANCER, 2021, 148 (10) : 2375 - 2388
  • [4] Structure and Function of Histone H3 Lysine 9 Methyltransferases and Demethylases
    Krishnan, Swathi
    Horowitz, Scott
    Trievel, Raymond C.
    CHEMBIOCHEM, 2011, 12 (02) : 254 - 263
  • [5] The emerging role of histone lysine demethylases in prostate cancer
    Crea, Francesco
    Sun, Lei
    Mai, Antonello
    Chiang, Yan Ting
    Farrar, William L.
    Danesi, Romano
    Helgason, Cheryl D.
    MOLECULAR CANCER, 2012, 11
  • [6] Targeting histone lysine demethylases - Progress, challenges, and the future
    Thinnes, Cyrille C.
    England, Katherine S.
    Kawamura, Akane
    Chowdhury, Rasheduzzaman
    Schofield, Christopher J.
    Hopkinson, Richard J.
    BIOCHIMICA ET BIOPHYSICA ACTA-GENE REGULATORY MECHANISMS, 2014, 1839 (12): : 1416 - 1432
  • [7] Histone lysine demethylases as targets for anticancer therapy
    Hojfeldt, Jonas W.
    Agger, Karl
    Helin, Kristian
    NATURE REVIEWS DRUG DISCOVERY, 2013, 12 (12) : 917 - 930
  • [8] Dynamic patterns of histone H3 lysine 4 methyltransferases and demethylases during mouse preimplantation development
    Shao, Gen-Bao
    Chen, Jun-Chao
    Zhang, Liu-Ping
    Huang, Pan
    Lu, Hong-Yan
    Jin, Jie
    Gong, Ai-Hua
    Sang, Jian-Rong
    IN VITRO CELLULAR & DEVELOPMENTAL BIOLOGY-ANIMAL, 2014, 50 (07) : 603 - 613
  • [9] Reversal of Histone Methylation: Biochemical and Molecular Mechanisms of Histone Demethylases
    Mosammaparast, Nima
    Shi, Yang
    ANNUAL REVIEW OF BIOCHEMISTRY, VOL 79, 2010, 79 : 155 - 179
  • [10] Developmental roles of the histone lysine demethylases
    Nottke, Amanda
    Colaiacovo, Monica P.
    Shi, Yang
    DEVELOPMENT, 2009, 136 (06): : 879 - 889