Understanding the Relationship Between Age and Thyroid Cancer

被引:97
|
作者
Haymart, Megan R. [1 ,2 ]
机构
[1] Univ Wisconsin, Div Endocrinol Diabet & Metab, Clin Sci Ctr H4 568, Dept Med, Madison, WI 53792 USA
[2] Univ Wisconsin, Paul P Carbone Comprehens Canc Ctr, Madison, WI 53792 USA
关键词
Thyroid cancer; Age; Prognostic indicators; Cancer stage; RECOMBINANT HUMAN THYROTROPIN; LYMPH-NODE METASTASES; PROGNOSTIC-FACTORS; RADIOIODINE ABLATION; RADIOACTIVE IODINE; SERUM THYROTROPIN; PAPILLARY; CARCINOMA; EXPRESSION; MANAGEMENT;
D O I
10.1634/theoncologist.2008-0194
中图分类号
R73 [肿瘤学];
学科分类号
100214 ;
摘要
Unique among malignancies, age is a key prognostic indicator for well-differentiated thyroid cancer. Patients aged <45 years can have the same degree of disease involvement and a distinctly different prognosis than those aged >45. Although the reason for the association between age and outcome is not entirely clear, it does imply that there is something intrinsic to either the cancer or the treatment that is age dependent. This article explores the characteristics of the normal thyroid and thyroid cancer that are age dependent. It then provides theories for the relationship between advanced age and poor prognosis, in addition to treatment options tailored to age at diagnosis. The Oncologist 2009; 14: 216-221
引用
收藏
页码:216 / 221
页数:6
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