Susceptibility to severe COVID-19

被引：47

作者：

Beck, David B. ^{[1
]}

Aksentijevich, Ivona ^{[1
]}

机构：

[1] NHGRI, Inflammatory Dis Sect, NIH, Bethesda, MD 20892 USA

来源：

SCIENCE | 2020年 / 370卷 / 6515期

关键词：

D O I：

10.1126/science.abe7591

中图分类号：

O [数理科学和化学]; P [天文学、地球科学]; Q [生物科学]; N [自然科学总论];

学科分类号：

07 ; 0710 ; 09 ;

摘要：

Genetic variants and autoantibodies that suppress antiviral immunity are linked to severe COVID-19

引用

页码：404 / 405

页数：4

共 15 条

[1] Systems biological assessment of immunity to mild versus severe COVID-19 infection in humans [J].

Arunachalam, Prabhu S. ;

Wimmers, Florian ;

Mok, Chris Ka Pun ;

Perera, Ranawaka A. P. M. ;

Scott, Madeleine ;

Hagan, Thomas ;

Sigal, Natalia ;

Feng, Yupeng ;

Bristow, Laurel ;

Tsang, Owen Tak-Yin ;

Wagh, Dhananjay ;

Coller, John ;

Pellegrini, Kathryn L. ;

Kazmin, Dmitri ;

Alaaeddine, Ghina ;

Leung, Wai Shing ;

Chan, Jacky Man Chun ;

Chik, Thomas Shiu Hong ;

Choi, Chris Yau Chung ;

Huerta, Christopher ;

McCullough, Michele Paine ;

Lv, Huibin ;

Anderson, Evan ;

Edupuganti, Srilatha ;

Upadhyay, Amit A. ;

Bosinger, Steve E. ;

Maecker, Holden Terry ;

Khatri, Purvesh ;

Rouphael, Nadine ;

Peiris, Malik ;

Pulendran, Bali .

SCIENCE, 2020, 369 (6508) :1210-+

[2] Autoantibodies against type I IFNs in patients with life-threatening COVID-19 [J].

Bastard, Paul ;

Rosen, Lindsey B. ;

Zhang, Qian ;

Michailidis, Eleftherios ;

Hoffmann, Hans-Heinrich ;

Zhang, Yu ;

Dorgham, Karim ;

Philippot, Quentin ;

Rosain, Jeremie ;

Beziat, Vivien ;

Manry, Jeremy ;

Shaw, Elana ;

Haljasmagi, Liis ;

Peterson, Part ;

Lorenzo, Lazaro ;

Bizien, Lucy ;

Trouillet-Assant, Sophie ;

Dobbs, Kerry ;

de Jesus, Adriana Almeida ;

Belot, Alexandre ;

Kallaste, Anne ;

Catherinot, Emilie ;

Tandjaoui-Lambiotte, Yacine ;

Le Pen, Jeremie ;

Kerner, Gaspard ;

Bigio, Benedetta ;

Seeleuthner, Yoann ;

Yang, Rui ;

Bolze, Alexandre ;

Spaan, Andras N. ;

Delmonte, Ottavia M. ;

Abers, Michael S. ;

Aiuti, Alessandro ;

Casari, Giorgio ;

Lampasona, Vito ;

Piemonti, Lorenzo ;

Ciceri, Fabio ;

Bilguvar, Kaya ;

Lifton, Richard P. ;

Vasse, Marc ;

Smadja, David M. ;

Migaud, Melanie ;

Hadjadj, Jerome ;

Terrier, Benjamin ;

Duffy, Darragh ;

Quintana-Murci, Lluis ;

van de Beek, Diederik ;

Roussel, Lucie ;

Vinh, Donald C. ;

Tangye, Stuart G. .

SCIENCE, 2020, 370 (6515) :423-+

[3] A Randomized Clinical Trial of the Efficacy and Safety of Interferon β-1a in Treatment of Severe COVID-19 [J].

Davoudi-Monfared, Effat ;

Rahmani, Hamid ;

Khalili, Hossein ;

Hajiabdolbaghi, Mahboubeh ;

Salehi, Mohamadreza ;

Abbasian, Ladan ;

Kazemzadeh, Hossein ;

Yekaninejad, Mir Saeed .

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY, 2020, 64 (09)

[4] Targets of T Cell Responses to SARS-CoV-2 Coronavirus in Humans with COVID-19 Disease and Unexposed Individuals [J].

Grifoni, Alba ;

Weiskopf, Daniela ;

Ramirez, Sydney, I ;

Mateus, Jose ;

Dan, Jennifer M. ;

Moderbacher, Carolyn Rydyznski ;

Rawlings, Stephen A. ;

Sutherland, Aaron ;

Premkumar, Lakshmanane ;

Jadi, Ramesh S. ;

Marrama, Daniel ;

de Silva, Aravinda M. ;

Frazier, April ;

Carlin, Aaron F. ;

Greenbaum, Jason A. ;

Peters, Bjoern ;

Krammer, Florian ;

Smith, Davey M. ;

Crotty, Shane ;

Sette, Alessandro .

CELL, 2020, 181 (07) :1489-+

[5] Mapping Systemic Inflammation and Antibody Responses in Multisystem Inflammatory Syndrome in Children (MIS-C) [J].

Gruber, Conor N. ;

Patel, Roosheel S. ;

Trachtman, Rebecca ;

Lepow, Lauren ;

Amanat, Fatima ;

Krammer, Florian ;

Wilson, Karen M. ;

Onel, Kenan ;

Geanon, Daniel ;

Tuballes, Kevin ;

Patel, Manishkumar ;

Mouskas, Konstantinos ;

O'Donnell, Timothy ;

Merritt, Elliot ;

Simons, Nicole W. ;

Barcessat, Vanessa ;

Del Valle, Diane M. ;

Udondem, Samantha ;

Kang, Gurpawan ;

Gangadharan, Sandeep ;

Ofori-Amanfo, George ;

Laserson, Uri ;

Rahman, Adeeb ;

Kim-Schulze, Seunghee ;

Charney, Alexander W. ;

Gnjatic, Sacha ;

Gelb, Bruce D. ;

Merad, Miriam ;

Bogunovic, Dusan .

CELL, 2020, 183 (04) :982-+

[6] Impaired type I interferon activity and inflammatory responses in severe COVID-19 patients [J].

Hadjadj, Jerome ;

Yatim, Nader ;

Barnabei, Laura ;

Corneau, Aurelien ;

Boussier, Jeremy ;

Smith, Nikaia ;

Pere, Helene ;

Charbit, Bruno ;

Bondet, Vincent ;

Chenevier-Gobeaux, Camille ;

Breillat, Paul ;

Carlier, Nicolas ;

Gauzit, Remy ;

Morbieu, Caroline ;

Pene, Frederic ;

Marin, Nathalie ;

Roche, Nicolas ;

Szwebel, Tali-Anne ;

Merkling, Sarah H. ;

Treluyer, Jean-Marc ;

Veyer, David ;

Mouthon, Luc ;

Blanc, Catherine ;

Tharaux, Pierre-Louis ;

Rozenberg, Flore ;

Fischer, Alain ;

Duffy, Darragh ;

Rieux-Laucat, Frederic ;

Kerneis, Solen ;

Terrier, Benjamin .

SCIENCE, 2020, 369 (6504) :718-+

[7] Longitudinal Isolation of Potent Near-Germline SARS-CoV-2-Neutralizing Antibodies from COVID-19 Patients [J].

Kreer, Christoph ;

Zehner, Matthias ;

Weber, Timm ;

Ercanoglu, Meryem S. ;

Gieselmann, Lutz ;

Rohde, Cornelius ;

Halwe, Sandro ;

Korenkov, Michael ;

Schommers, Philipp ;

Vanshylla, Kanika ;

Di Cristanziano, Veronica ;

Janicki, Hanna ;

Brinker, Reinhild ;

Ashurov, Artem ;

Kraehling, Verena ;

Kupke, Alexandra ;

Cohen-Dvashi, Hadas ;

Koch, Manuel ;

Eckert, Jan Mathis ;

Lederer, Simone ;

Pfeifer, Nico ;

Wolf, Timo ;

Vehreschild, Maria J. G. T. ;

Wendtner, Clemens ;

Diskin, Ron ;

Gruell, Henning ;

Becker, Stephan ;

Klein, Florian .

CELL, 2020, 182 (04) :843-+

[8] Autoantibodies against cytokines: phenocopies of primary immunodeficiencies? [J].

Ku, Chen-Lung ;

Chi, Chih-Yu ;

von Bernuth, Horst ;

Doffinger, Rainer .

HUMAN GENETICS, 2020, 139 (6-7) :783-794

[9] The type I interferon response in COVID-19: implications for treatment [J].

Lee, Jeong Seok ;

Shin, Eui-Cheol .

NATURE REVIEWS IMMUNOLOGY, 2020, 20 (10) :585-586

[10] The Role of Host Genetic Factors in Coronavirus Susceptibility: Review of Animal and Systematic Review of Human Literature [J].

LoPresti, Marissa ;

Beck, David B. ;

Duggal, Priya ;

Cummings, Derek A. T. ;

Solomon, Benjamin D. .

AMERICAN JOURNAL OF HUMAN GENETICS, 2020, 107 (03) :381-402

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