Cardiac Remodeling Patterns in Severe Obesity According to Arterial Hypertension Grade

被引:6
作者
de Cleva, Roberto [1 ,2 ]
Araujo, Victor Arrais [1 ]
Ornelas Buchalla, Carla Cristina [1 ]
Costa, Fabio de Oliveira [1 ]
Cardoso, Acacio Fernandes [1 ]
Pajecki, Denis [1 ]
Santo, Marco Aurelio [1 ]
机构
[1] Univ Sao Paulo, Hosp Clin, Dept Gastroenterol, Sch Med, AVe Dr Arnaldo 455, BR-01246000 Sao Paulo, SP, Brazil
[2] Rua Cel Artur Godoi 125,Apto 152, BR-04018050 Sao Paulo, SP, Brazil
基金
巴西圣保罗研究基金会;
关键词
Severe obesity; Hypertension; Left ventricular hypertrophy; LEFT-VENTRICULAR MASS; PROGNOSTIC-SIGNIFICANCE; NONHEMODYNAMIC FACTORS; SYSTOLIC FUNCTION; MORBID-OBESITY; HYPERTROPHY; GEOMETRY; RISK; ECHOCARDIOGRAPHY; EPIDEMIOLOGY;
D O I
10.1007/s11695-017-2968-z
中图分类号
R61 [外科手术学];
学科分类号
摘要
The purpose of this study is to correlate the left ventricular hypertrophy (LVH) patterns according to severe obesity and arterial hypertension (AHT) grades. A cross-sectional prospective study was conducted in 379 patients with severe obesity. Obesity was classified according to the BMI in the following: morbidly obese (MO; 40 < BMI < 50 kg/m(2)) and super obese (SO; BMI > 50 kg/m(2)). The AHT was classified into classes 1 and 2 according to American Heart Association. The presence of LVH and the pattern of cardiac remodeling were determined by transthoracic echocardiography. LVH was present in 58.6% of patients. Obesity and AHT had additive effects in LVH prevalence. LVH was found in 32.9 and 46.7% of MO with AHT grades 1 and 2, respectively. LVH was diagnosed in 39.1% in SO with AHT grade 1 and in 50% of AHT grade 2. Patients with AHT presented a significantly higher risk of developing LVH (OR 1.97; p = 0.003). Hypertension grade was also a determinant variable in the development of LVH. Patients with AHT 2 had 4.31-fold greater risk (p < 0.001) when compared to normotensive patients. BMI was only considered an independent risk factor for LVH in patients with BMI greater than 47.17 kg/m(2) (OR 1.62; p = 0.023). AHT is a stronger predictive factor of LVH than obesity grade.
引用
收藏
页码:1047 / 1054
页数:8
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