Discrimination of Flavonoids by a Hypothesis Free Sensor Array

被引：23

作者：

Huang, Wei ^{[1
]}

Seehafer, Kai ^{[1
]}

Bunz, Uwe H. F. ^{[1
,2
]}

机构：

[1] Heidelberg Univ, Organ Chem Inst, Neuenheimer Feld 270, D-69120 Heidelberg, Germany

[2] Heidelberg Univ, CAM, Neuenheimer Feld 225, D-69120 Heidelberg, Germany

来源：

ACS APPLIED POLYMER MATERIALS | 2019年 / 1卷 / 06期

关键词：

fluorescent polymers; flavonoids; sensor array; linear discriminant analysis; discrimination; IDENTIFICATION;

D O I：

10.1021/acsapm.9b00116

中图分类号：

T [工业技术];

学科分类号：

08 ;

摘要：

Flavonoids are the most abundant polyphenols in the human diet and are ascribed a potentially beneficial effect against cancers, diabetes, and oxidative stress. The broad range of bioactivities and number of different flavonoids in a multitude of commercial products dictate a need to discriminate among different flavonoids as a means of quality control and testing for commercial flavonoid tablets, capsules, powders, etc. A sensor array has been constructed and optimized using five different fluorescent polymers, including poly(para-phenyleneethynylene)s (PPE) and poly(tetraphenylethene)s (PTPEs), employed at different pH values (4, 7, and 10). The selected six element array discriminates 11 different sample flavonoids from six different subgroups with 100% accuracy. Six commercial nutrition products were also successfully investigated to demonstrate the practical application of the sensor array. This array allows to inspect the quality of nutrition products with respect to content and identity.

引用

页码：1301 / 1307

页数：13

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