Synthesis and biological evaluation of some new chalcones and their derivatives

被引：0

作者：

Solankee, A ^{[1
]}

Kapadia, K ^{[1
]}

Thakor, I ^{[1
]}

Patel, J ^{[1
]}

Lad, S ^{[1
]}

机构：

[1] BKM Sci Coll, Dept Chem, Valsad 396001, India

来源：

ASIAN JOURNAL OF CHEMISTRY | 2004年 / 16卷 / 02期

关键词：

synthesis; chalcones; pyrazolines; pyrimidinethiones; antibacterial activity;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Some new chalcones have been prepared by the Claisen-Schmidt condensation between ketone and different aldehydes. Further chalcones on cyclocondensation with phenylhydrazine hydrochloride and thiourea in presence of alkali give pyrazolines and pyrimidinethiones respectively. The constitution of the synthesized products have been characterized by elemental analysis, IR and PMR spectral data. The products have been screened for their in vitro biological assay like antibacterial activity.

引用

页码：921 / 927

页数：7

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