Asymmetric synthesis of alkaloids using polyfunctionalized chiral building blocks

被引：22

作者：

Davis, FA ^{[1
]}

Chao, B ^{[1
]}

Andemichael, YW ^{[1
]}

Mohanty, PK ^{[1
]}

Fang, TN ^{[1
]}

Burns, DM ^{[1
]}

Rao, A ^{[1
]}

Szewczyk, JM ^{[1
]}

机构：

[1] Temple Univ, Dept Chem, Philadelphia, PA 19122 USA

来源：

HETEROATOM CHEMISTRY | 2002年 / 13卷 / 05期

关键词：

D O I：

10.1002/hc.10090

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Enantiopure N-sulfinyl-delta-amino-beta-ketoesters and isoquinolones, prepared from sulfinimines (N-sulfinyl imines) are a new class of polyfunctionalized chiral building blocks. These building blocks provide easy access to enantiomerically pure, functionalized piperidines and tetrahydroisoquinolines with a minimum of chemical manipulation and protecting-group chemistry. (C) 2002 Wiley Periodicals, Inc.

引用

收藏

页码：486 / 492

页数：7

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