Asymmetric synthesis of alkaloids using polyfunctionalized chiral building blocks

被引:22
作者
Davis, FA [1 ]
Chao, B [1 ]
Andemichael, YW [1 ]
Mohanty, PK [1 ]
Fang, TN [1 ]
Burns, DM [1 ]
Rao, A [1 ]
Szewczyk, JM [1 ]
机构
[1] Temple Univ, Dept Chem, Philadelphia, PA 19122 USA
关键词
D O I
10.1002/hc.10090
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
Enantiopure N-sulfinyl-delta-amino-beta-ketoesters and isoquinolones, prepared from sulfinimines (N-sulfinyl imines) are a new class of polyfunctionalized chiral building blocks. These building blocks provide easy access to enantiomerically pure, functionalized piperidines and tetrahydroisoquinolines with a minimum of chemical manipulation and protecting-group chemistry. (C) 2002 Wiley Periodicals, Inc.
引用
收藏
页码:486 / 492
页数:7
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