Successful Recovery from COVID-19-associated Acute Respiratory Failure with Polymyxin B-immobilized Fiber Column-direct Hemoperfusion

被引：7

作者：

Kusaba, Yusaku ^{[1
]}

Izumi, Shinyu ^{[1
]}

Takasaki, Jin ^{[1
]}

Suzuki, Manabu ^{[1
]}

Katagiri, Daisuke ^{[2
]}

Katsuno, Takashi ^{[1
]}

Matsumoto, Shuichiro ^{[1
]}

Sakamoto, Keita ^{[1
]}

Hashimoto, Masao ^{[1
]}

Ohmagari, Norio ^{[3
]}

Katano, Harutaka ^{[4
]}

Suzuki, Tadaki ^{[4
]}

Hojo, Masayuki ^{[1
]}

Sugiyama, Haruhito ^{[1
]}

机构：

[1] Natl Ctr Global Hlth & Med, Dept Resp Med, Tokyo, Japan

[2] Natl Ctr Global Hlth & Med, Dept Nephrol, Tokyo, Japan

[3] Natl Ctr Global Hlth & Med, Dis Control & Prevent Ctr, Tokyo, Japan

[4] Natl Inst Infect Dis, Dept Pathol, Tokyo, Japan

来源：

INTERNAL MEDICINE | 2020年 / 59卷 / 19期

关键词：

COVID-19; SARS-CoV-2; acute respiratory failure; polymyxin B-immobilized fiber column-direct hemoperfusion; IDIOPATHIC PULMONARY-FIBROSIS; ACUTE EXACERBATION; ADSORPTION;

D O I：

10.2169/internalmedicine.5413-20

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

An 83-year-old man was hospitalized for coronavirus disease 2019 (COVID-19) after a 10-day history of a persistent fever. Chest computed tomography showed extensive non-segmental ground glass opacity. Despite the initiation of lopinavir and ritonavir, respiratory failure progressed. Two days of polymyxin B-immobilized fiber column-direct hemoperfusion (PMX-DHP) with adjunctive corticosteroid prevented his respiratory condition from worsening. For rapidly progressive COVID-19 cases, the early use of PMX-DHP may avoid the need for mechanical ventilation by suppressing local inflammation of the lung.

引用

页码：2405 / 2408

页数：4

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