Two new eupodienone lignans from Gymnotheca chinensis

被引：16
作者：
Xiao, Shi-Ji [1 ,2 ]
Chen, Fang [2 ]
Ding, Li-Sheng [1 ]
Zhou, Yan [1 ]
机构：
[1] Chinese Acad Sci, Chengdu Inst Biol, Key Lab Mt Ecol Restorat & Bioresource Utilizat, Chengdu 610041, Peoples R China
[2] Sichuan Univ, Coll Life Sci, Chengdu 610064, Peoples R China
来源：
CHINESE CHEMICAL LETTERS | 2014年 / 25卷 / 03期
关键词：
Gymnotheca chinensis; Saururaceae; Eupodienone; Lignan; EUPOMATIA-BENNETTII; CONSTITUENTS;
D O I：
10.1016/j.cclet.2013.11.053
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Two new eupodienone lignans, named gymnothelignan T (1) and gymnothelignan U (2) were isolated from the whole plants of endemic medicinal plant of Gymnotheca chinensis (Saururaceae). The structures of the new compounds were elucidated by means of HRMS, 1D and 2D NMR. Compound 1 was tested for cytotoxic activity in HCT15, HCT116, A549, MCF-7 and HepG2 cells and exhibited no appreciable activity against these tested cell lines with IC50 values above 50 mu mol/L. (C) 2013 Li-Sheng Ding and Yan Zhou. Published by Elsevier B.V. on behalf of Chinese Chemical Society. All rights reserved.
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收藏
页码：463 / 464
页数：2
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