Lysophosphatidic acid: G-protein signalling and cellular responses

被引：468
作者：
Moolenaar, WH
Kranenburg, O
Postma, FR
Zondag, GCM
机构：
[1] Division of Cellular Biochemistry, Netherlands Cancer Institute, 1066 X Amsterdam
来源：
CURRENT OPINION IN CELL BIOLOGY | 1997年 / 9卷 / 02期
关键词：
D O I：
10.1016/S0955-0674(97)80059-2
中图分类号：
Q2 [细胞生物学];
学科分类号：
071009 ; 090102 ;
摘要：
Lysophosphatidic acid (LPA) is a serum-borne phospholipid that activates a specific G protein coupled receptor to evoke multiple cellular responses. Recent work has identified two cDNAs encoding putative LPA receptors, Various LPA-like agonists that act on distinct receptors, and new pathways that link the receptor(s) to such diverse events as Ras signalling, cytoskeletal remodelling and membrane depolarization.
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收藏
页码：168 / 173
页数：6
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