Botanical Drugs as an Emerging Strategy in Inflammatory Bowel Disease: A Review

被引：50

作者：

Algieri, Francesca ^{[1
]}

Rodriguez-Nogales, Alba ^{[1
]}

Elena Rodriguez-Cabezas, M. ^{[1
]}

Risco, Severiano ^{[1
]}

Angeles Ocete, M. ^{[1
]}

Galvez, Julio ^{[1
]}

机构：

[1] Univ Granada, Dept Pharmacol, Ctr Biomed Res CIBM, CIBER EHD,Ibs GRANADA, Granada 18016, Spain

来源：

MEDIATORS OF INFLAMMATION | 2015年 / 2015卷

关键词：

NF-KAPPA-B; WORMWOOD ARTEMISIA-ABSINTHIUM; ALTERNATIVE MEDICINE USE; CELL-ADHESION MOLECULES; GROWTH-FACTOR-BETA; BOSWELLIA-SERRATA; ANDROGRAPHIS-PANICULATA; CROHNS-DISEASE; DOUBLE-BLIND; ULCERATIVE-COLITIS;

D O I：

10.1155/2015/179616

中图分类号：

Q2 [细胞生物学];

学科分类号：

071009 ; 090102 ;

摘要：

Crohn's disease and ulcerative colitis are the two most common categories of inflammatory bowel disease (IBD), which are characterized by chronic inflammation of the intestine that comprises the patients' life quality and requires sustained pharmacological and surgical treatments. Since their aetiology is not completely understood, nonfully efficient drugs have been developed and those that show effectiveness are not devoid of quite important adverse effects that impair their long-term use. Therefore, many patients try with some botanical drugs, which are safe and efficient after many years of use. However, it is necessary to properly evaluate these therapies to consider a new strategy for human IBD. In this report we have reviewed the main botanical drugs that have been assessed in clinical trials in human IBD and the mechanisms and the active compounds proposed for their beneficial effects.

引用

页数：14

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