Evaluation of short-term outcomes of laparoscopic-assisted surgery for colorectal cancer in elderly patients aged over 75 years old: a multi-institutional study (YSURG1401)

被引:31
作者
Kazama, Keisuke [1 ]
Aoyama, Toru [1 ]
Hayashi, Tsutomu [1 ]
Yamada, Takanobu [1 ]
Numata, Masakatsu [1 ]
Amano, Shinya [1 ]
Kamiya, Mariko [1 ]
Sato, Tsutomu [1 ]
Yoshikawa, Takaki [2 ]
Shiozawa, Manabu [2 ]
Oshima, Takashi [1 ]
Yukawa, Norio [1 ]
Rino, Yasushi [1 ]
Masuda, Munetaka [1 ]
机构
[1] Yokohama City Univ Med, Dept Surg, Kanazawa Ku, 3-9 Fukuura, Yokohama, Kanagawa 2360004, Japan
[2] Kanagawa Canc Ctr, Dept Gastrointestinal Surg, Yokohama, Kanagawa 2418515, Japan
关键词
Corolectal cancer; Lapaloscopic surgery; Elderly patient; Safety; Feasibility; MRC CLASICC TRIAL; COLON-CANCER; RANDOMIZED-TRIAL; COMPLICATIONS; COLECTOMY; RESECTION;
D O I
10.1186/s12893-017-0229-7
中图分类号
R61 [外科手术学];
学科分类号
摘要
Background: The short-term outcomes of laparoscopic-assisted surgery for colorectal cancer (LAC) have not been fully evaluated in elderly patients. The aim of this study was to compare the short term surgical outcomes of LAC between the patients older than 75 years and those with non-elderly patients. Methods: This retrospective multi-institutional study selected patients who underwent LAC between April 2013 and March 2014 at Yokohama City University Hospital and its related general hospitals. The patients were categorized into two groups: elderly patients (> 75 years of age: group A) and non-elderly patients (< 75 years of age: group B). Surgical outcomes and post operative complications were compared between the two groups. Results: A total of 237 patients were evaluated in the present study. Eighty-four patients were classified into group A, and 153 into group B. Preoperative clinicopathological outcomes demonstrated no significant differences except for the ASA score. When comparing the surgical outcomes between group A and group B, the rate of conversion to open procedure (3.6% vs 5.2%, P = 0.750), median operation time (232 min vs 232 min, P = 0.320), median blood loss (20 ml vs 12 ml, P = 0.350). The differences were not significantly different in the surgical outcomes. The incidences of > grade 2 post operative surgical complications were similar between two groups ((19.0% vs 15.7%, p = 0.587). No mortality was observed in this study. The length of postoperative hospital stay was also similar (10 days vs 10 days, p = 0.350). Conclusions: The present study suggested that LAC is safe and feasible, regardless of the age of the patient, especially for elderly patients who may be candidates for colon cancer surgery.
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共 33 条
[1]  
[Anonymous], JAMA
[2]   Role of surgery for colorectal cancer in the elderly [J].
Biondi, Antonio ;
Vacante, Marco ;
Ambrosino, Immacolata ;
Cristaldi, Erika ;
Pietrapertosa, Giuseppe ;
Basile, Francesco .
WORLD JOURNAL OF GASTROINTESTINAL SURGERY, 2016, 8 (09) :606-613
[3]   Predictors of Conversion in Laparoscopic-assisted Colectomy for Colorectal Cancer and Clinical Outcomes [J].
Biondi, Antonio ;
Grosso, Giuseppe ;
Mistretta, Antonio ;
Marventano, Stefano ;
Tropea, Alessandro ;
Gruttadauria, Salvatore ;
Basile, Francesco .
SURGICAL LAPAROSCOPY ENDOSCOPY & PERCUTANEOUS TECHNIQUES, 2014, 24 (01) :E21-E26
[4]   Laparoscopic vs. open approach for colorectal cancer: evolution over time of minimal invasive surgery [J].
Biondi, Antonio ;
Grosso, Giuseppe ;
Mistretta, Antonio ;
Marventano, Stefano ;
Toscano, Chiara ;
Drago, Filippo ;
Gangi, Santi ;
Basile, Francesco .
BMC SURGERY, 2013, 13
[5]   Laparoscopic-Assisted Versus Open Surgery for Colorectal Cancer: Short- and Long-Term Outcomes Comparison [J].
Biondi, Antonio ;
Grosso, Giuseppe ;
Mistretta, Antonio ;
Marventano, Stefano ;
Toscano, Chiara ;
Gruttadauria, Salvatore ;
Basile, Francesco .
JOURNAL OF LAPAROENDOSCOPIC & ADVANCED SURGICAL TECHNIQUES, 2013, 23 (01) :1-7
[6]   A Randomized Trial of Laparoscopic versus Open Surgery for Rectal Cancer [J].
Bonjer, H. Jaap ;
Deijen, Charlotte L. ;
Abis, Gabor A. ;
Cuesta, Miguel A. ;
van der Pas, Martijn H. G. M. ;
de lange-de Klerk, Elly S. M. ;
Lacy, Antonio M. ;
Bemelman, Willem A. ;
Andersson, John ;
Angenete, Eva ;
Rosenberg, Jacob ;
Fuerst, Alois ;
Haglind, Eva .
NEW ENGLAND JOURNAL OF MEDICINE, 2015, 372 (14) :1324-1332
[7]   Laparoscopic surgery versus open surgery for colon cancer:: short-term outcomes of a randomised trial [J].
Bonjer, HJ ;
Haglind, E ;
Jeekel, I ;
Kazemier, G ;
Páhlman, L ;
Hop, WCJ ;
Veldkamp, R ;
Kuhry, E ;
Haglind, E ;
Pahlman, L ;
Cuesta, MA ;
Msika, S ;
Morino, M ;
Lacy, A ;
Jeekel, I .
LANCET ONCOLOGY, 2005, 6 (07) :477-484
[8]   Laparoscopic colorectal surgery in elderly patients: A matched case-control study in 178 patients [J].
Chautard, Julien ;
Alves, Arnaud ;
Zalinski, Stephane ;
Bretagnol, Frederic ;
Valleur, Patrice ;
Panis, Yves .
JOURNAL OF THE AMERICAN COLLEGE OF SURGEONS, 2008, 206 (02) :255-260
[9]   Classification of surgical complications - A new proposal with evaluation in a cohort of 6336 patients and results of a survey [J].
Dindo, D ;
Demartines, N ;
Clavien, PA .
ANNALS OF SURGERY, 2004, 240 (02) :205-213
[10]   Cancer incidence and mortality worldwide: Sources, methods and major patterns in GLOBOCAN 2012 [J].
Ferlay, Jacques ;
Soerjomataram, Isabelle ;
Dikshit, Rajesh ;
Eser, Sultan ;
Mathers, Colin ;
Rebelo, Marise ;
Parkin, Donald Maxwell ;
Forman, David ;
Bray, Freddie .
INTERNATIONAL JOURNAL OF CANCER, 2015, 136 (05) :E359-E386