Synthesis of 2,4-and 2,4,5-substituted oxazoles via a silver triflate mediated cyclization

被引：17
作者：
Bailey, Jessica L. [1 ]
Sudini, Ravinder R. [1 ]
机构：
[1] GlaxoSmithKline, King Of Prussia, PA 19406 USA
来源：
TETRAHEDRON LETTERS | 2014年 / 55卷 / 27期
关键词：
Oxazole; Silver triflate; Cyclization; Bromo-ketone; Amide; ONE-STEP SYNTHESIS; 2,5-DISUBSTITUTED OXAZOLES; OXIDATIVE CYCLIZATION; CATALYZED CYCLIZATION; EFFICIENT SYNTHESIS; COPPER; PROPARGYLAMIDES; ENAMIDES; DERIVATIVES; CONVERSION;
D O I：
10.1016/j.tetlet.2014.05.002
中图分类号：
O62 [有机化学];
学科分类号：
070303 ; 081704 ;
摘要：
2,4- and 2,4,5-substituted oxazoles were prepared from a broad range of bromo-ketones and amides in high yield and purity. (C) 2014 Elsevier Ltd. All rights reserved.
引用
收藏
页码：3674 / 3677
页数：4
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