Synthesis of racemic brevioxime

被引：18

作者：

Clive, DLJ ^{[1
]}

Hisaindee, S ^{[1
]}

机构：

[1] Univ Alberta, Dept Chem, Edmonton, AB T6G 2G2, Canada

来源：

CHEMICAL COMMUNICATIONS | 1999年 / 22期

关键词：

D O I：

10.1039/a906579b

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

Amine hydrochloride 12 and beta-keto thioester 16 were coupled and treated with TFA; the resulting alcohols 18 were oxidized and converted into a mixture of oximes 20, from which the major product, racemic brevioxime 1, was isolated.

引用

页码：2251 / 2252

页数：2

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