Antibacterial efficacy of facile cyanobacterial silver nanoparticles inferred by antioxidant mechanism

被引:49
|
作者
Husain, Shaheen [1 ]
Verma, Suresh K. [2 ]
Hemlata [1 ]
Azam, Mudsser [1 ]
Sardar, Meryam [3 ]
Haq, Q. M. R. [4 ]
Fatma, Tasneem [1 ]
机构
[1] Jamia Millia Islamia, Dept Biosci, Cyanobacterial Biotechnol Lab, New Delhi, India
[2] KIIT Univ, Sch Biotechnol, Bhubaneswar, India
[3] Jamia Millia Islamia, Dept Biosci, Enzyme Technol Lab, New Delhi, India
[4] Jamia Millia Islamia, Dept Biosci, Mol Biol Lab, New Delhi, India
关键词
Green synthesis; Cyanobacteria; Silver nanoparticles; Antibacterial activity; Antioxidant activity; GREEN SYNTHESIS; FILAMENTOUS CYANOBACTERIA; BIOSYNTHESIS; PREVENTION; PARTICLES; EXTRACTS; NITRATE; COLI; SIZE;
D O I
10.1016/j.msec.2021.111888
中图分类号
TB3 [工程材料学]; R318.08 [生物材料学];
学科分类号
0805 ; 080501 ; 080502 ;
摘要
Nanoparticles (NPs) have gained importance in technological advances owing to their user friendly enhanced and efficient physical, chemical, and biological characteristics compared to their bulk counterparts. Biological synthesis of NPs by using a microorganism, enzymes, or plant extracts offers a greener and eco-friendly approach besides many advantages over physical or chemical approaches. This study reports the biosynthesis of silver nanoparticles (AgNPs) using Nostoc muscorum NCCU 442 aqueous extract as the reducing and capping agent for AgNPs synthesis. The synthesized nanoparticles were characterized by UV-VIS spectrum, SEM, EDS, TEM, AFM, DLS and XRD. Results showed distinguishing polycrystalline nature of synthesized AgNPs with surface plasmon significant band in the size range of 6-45nm with average 30 size nm. FT-IR study revealed the role of secondary metabolites present in aqueous extract for the synthesis of AgNPs. Biological activities of purified AgNPs as antioxidant and antibacterial potential showed the highest antibacterial activity against Staphylococcus aureus MTCC 902.
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页数:10
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