Middle ear adenoma with neuroendocrine differentiation (MEA-ND) in the pediatric population

被引:10
作者
Dogru, Salim [1 ]
Wilkinson, Eric P. [2 ]
Robinson, Robert A. [3 ]
Smith, Richard J. H. [4 ]
机构
[1] Haydarpasa Training Hosp, Dept Otolaryngol, TR-34668 Istanbul, Turkey
[2] House Clin, Los Angeles, CA USA
[3] Univ Iowa Hosp & Clin, Dept Pathol, Iowa City, IA 52242 USA
[4] Univ Iowa Hosp & Clin, Dept Otolaryngol Head & Neck Surg, Iowa City, IA 52242 USA
关键词
Adenoma; Middle ear; Carcinoid tumor; Neuroendocrine tumor; CARCINOID-TUMOR;
D O I
10.1016/j.ijporl.2009.02.014
中图分类号
R76 [耳鼻咽喉科学];
学科分类号
100213 ;
摘要
Middle ear adenoma with neuroendocrine differentiation is an uncommon tumor of the tympanic cavity. The terminology of this entity has suffered due to a poor understanding of the differentiation of these neoplasms, and has included both "adenoma" as well as "carcinoid tumor." Immunohistochemical techniques have helped clarify that these tumors all share elements of neuroendocrine differentiation. Occurrences of this tumor in the pediatric population are extremely rare. In the world literature, only three pediatric cases of middle ear adenoma with neuroendocrine differentiation have been described. We report the youngest case to date of middle ear adenoma with neuroendocrine differentiation, in a 13-year-old boy. We discuss the differential diagnosis, surgical management, and pathology of this entity. (C) 2009 Elsevier Ireland Ltd. All rights reserved.
引用
收藏
页码:895 / 898
页数:4
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