Biochemical Changes and Risk Factors in the Prognosis of Antibiotics Susceptibility in Urinary Tract Infections

被引：1

作者：

Vata, Andrei ^{[1
,2
]}

Hunea, Ioana Maria ^{[1
,2
]}

Dorneanu, Olivia ^{[1
,2
]}

Harja-Alexa, Ioana Alina ^{[1
]}

Plesca, Claudia ^{[1
]}

Leonte-Enache, Georgiana ^{[1
]}

Ciocan, Alexandra ^{[1
]}

Ghiciuc, Cristina Mihela ^{[1
]}

Esanu, Irina ^{[1
]}

Manolache, Mihai ^{[3
]}

Luca, Catalina Mihaela ^{[1
,2
]}

机构：

[1] Univ Med & Pharm Grigore T Popa, 16 Univ Str, Iasi 700115, Romania

[2] Hosp Infect Dis Sfanta Parascheva, 2 Octav Botez Str, Iasi 700116, Romania

[3] CEBIS Int SAGL, Via Magio 1C, CH-6900 Lugano, Switzerland

来源：

REVISTA DE CHIMIE | 2019年 / 70卷 / 05期

关键词：

complicated urinary tract infections; risk factors; multi - drug resistance; MULTICENTER;

D O I：

暂无

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

The aim of our study was evaluation of prevalence of uncomplicated and complicated urinary tract infections (UTIs) among patients with UTIs associated with Gram - negative bacteria and analysis of prognostic risk factors in complicated UTIs. We retrospectively analyzed the medical records of inpatients with diagnosis of UTI based on clinical, biological and microbiological assay. Susceptibility tests for different antimicrobial categories were performed. Risk factors in complicated UTIs were correlated with pathogens' susceptibility. A total of 96 eligible patients were analyzed. Complicated UTIs were identified in 66.67% cases. The most frequent uropathogens isolated were E.coli and Klebsiella species. Exrtrarenal factors and nephropathic disease were the most common factors associated with an increased prevalence of multi - drug resistant isolates. Knowledge of the spectrum of the possible pathogens and local resistance patterns are very important for the antibacterial treatment outcome.

引用

页码：1822 / 1825

页数：4

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