Two New Flavones from Hypericum chinense and Their Anti-Tobacco Mosaic Virus Activity

被引：4
作者：
Zhou, Bin [1 ,2 ]
Li, Yinke [1 ,2 ,3 ]
Wu, Xianxue [3 ]
Li, Ming [3 ]
Ye, Yanqing [1 ,2 ]
Gao, Xuemei [1 ,2 ]
Hu, Qiufen [1 ,2 ]
机构：
[1] State Ethn Affairs Commiss, Key Lab Chem Ethn Med Resources, Kunming 650031, Peoples R China
[2] Yunnan Univ Nat, Minist Educ, Kunming 650031, Peoples R China
[3] Yuxi Normal Univ, Coll Resource & Environm, Yuxi 653100, Peoples R China
来源：
CHEMISTRY OF NATURAL COMPOUNDS | 2015年 / 51卷 / 05期
基金：
中国国家自然科学基金;
关键词：
Hypericum chinense; flavones; anti-tobacco mosaic virus; ACYLPHLOROGLUCINOLS; XANTHONES; TOBACCO; ROOTS; GENUS; STEMS;
D O I：
10.1007/s10600-015-1429-y
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
Two new flavones, 6,4'-dimethoxy-8-formylflavone (1) and 6,7-dimethoxy-8-acetyl-4'-hydroxyflavone (2), together with five known flavones (3-7), were isolated from the leaves and stems of Hypericum chinense. The structure of 1-7 was elucidated by spectroscopic methods including extensive 1D and 2D NMR techniques. Compounds 1, 2, 6, and 7 were evaluated for their anti-tobacco mosaic virus (anti-TMV) activity. The results showed that compound 1 shows high anti-TMV activity with an inhibition rate of 31.4%, which is close to that of the positive control.
引用
收藏
页码：840 / 843
页数：4
相关论文
共 20 条
[1]   Prenylated Acylphloroglucinols, Chipericumins A-D, from Hypericum chinense [J].
Abe, Shuhei ;
Tanaka, Naonobu ;
Kobayashi, Jun'ichi .
JOURNAL OF NATURAL PRODUCTS, 2012, 75 (03) :484-488
[2]  
Avato P, 2005, STUD NAT PROD CHEM, V30, P603
[3]   Three new flavonoids from the leaves of oriental tobacco and their cytotoxicity [J].
Chen, Jinxiong ;
Leng, Hongqiong ;
Duan, Yuanxing ;
Zhao, Wei ;
Yang, Guangyu ;
Guo, Yadong ;
Chen, Yongkuan ;
Hu, Qiufen .
PHYTOCHEMISTRY LETTERS, 2013, 6 (01) :144-147
[4]   Isoflavones from the roots and stems of Nicotiana Tabacum and their anti-tobacco mosaic virus activities [J].
Chen, Zhangyu ;
Tan, Jianlin ;
Yang, Guangyu ;
Miao, Mingming ;
Chen, Yongkuan ;
Li, Tianfei .
PHYTOCHEMISTRY LETTERS, 2012, 5 (02) :233-235
[5]   The genus Hypericum -: a valuable resource of anti-Staphylococcal leads [J].
Gibbons, S ;
Ohlendorf, B ;
Johnsen, I .
FITOTERAPIA, 2002, 73 (04) :300-304
[6]   Cytotoxic Oxepinochromenone and Flavonoids from the Flower Buds of Rosa rugosa [J].
Hu, Qiu-Fen ;
Zhou, Bin ;
Huang, Jian-Ming ;
Jiang, Zhi-Yong ;
Huang, Xiang-Zhong ;
Yang, Li-Ying ;
Gao, Xue-Mei ;
Yang, Guang-Yu ;
Che, Chun-Tao .
JOURNAL OF NATURAL PRODUCTS, 2013, 76 (10) :1866-1871
[7]   Antiviral Phenolic Compounds from Arundina gramnifolia [J].
Hu, Qiu-Fen ;
Zhou, Bin ;
Huang, Jian-Ming ;
Gao, Xue-Mei ;
Shu, Li-Dan ;
Yang, Guang-Yu ;
Che, Chun-Tao .
JOURNAL OF NATURAL PRODUCTS, 2013, 76 (02) :292-296
[8]   Antiviral Chromones from the Stem of Cassia siamea [J].
Hu, Qiu-Fen ;
Zhou, Bin ;
Gao, Xue-Mei ;
Yang, Li-Ying ;
Shu, Li-Dan ;
Shen, Yanqiong ;
Li, Gan-Peng ;
Che, Chun-Tao ;
Yang, Guang-Yu .
JOURNAL OF NATURAL PRODUCTS, 2012, 75 (11) :1909-1914
[9]   Evaluation of the Antiviral Activity of Extracts from Plants Grown in the Qinling Region of China Against Infection by Tobacco mosaic virus (TMV) [J].
Jing, Bingnian ;
Ma, Zhiqing ;
Feng, Juntao ;
Liang, Hongyan ;
Li, Chen ;
Zhang, Xing .
JOURNAL OF PHYTOPATHOLOGY, 2012, 160 (04) :181-186
[10]   8-C-PRENYLFLAVONOIDS FROM THE SEED OF TEPHROSIA-BRACTEOLATA [J].
KHALID, SA ;
WATERMAN, PG .
PHYTOCHEMISTRY, 1981, 20 (07) :1719-1720
12