Leishmanicidal activity of Pycnoporus sanguineus

被引：24
|
作者：
Correa, Edwin
Cardona, Diana
Quinones, Winston
Torres, Fernando
Franco, Ana E.
Velez, Ivan D.
Robledo, Sara
Echeverri, Fernando
机构：
[1] Univ Antioquia, Grp Quim Organ Prod Nat, SIU, Medellin, Colombia
[2] Univ Antioquia, Inst Biol, Medellin, Colombia
[3] Univ Antioquia, SIU, Programa Control & Estudio Enfermedades, Medellin, Colombia
来源：
PHYTOTHERAPY RESEARCH | 2006年 / 20卷 / 06期
关键词：
Pycnoporus sanguineus; ergosterol endoperoxide; leishmanicidal activity;
D O I：
10.1002/ptr.1890
中图分类号：
R914 [药物化学];
学科分类号：
100701 ;
摘要：
In the search for antiparasite compounds from the Colombian flora, an active compound against Leishmania (Viannia) panamensis amastigotes was isolated from the fungi Pycnoporus sanguineus. The structural elucidation was achieved with spectroscopic methods (H-1 and C-13 NMR and MS). This compound was identified as ergosterol 5,8-endoperoxide. Copyright (c) 2006 John Wiley & Sons, Ltd.
引用
收藏
页码：497 / 499
页数：3
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