Syndrome of Inappropriate Antidiuretic Hormone Secretion Following Liver Transplantation

被引:0
作者
Takagi, Kosei [1 ]
Yagi, Takahito [1 ]
Shinoura, Susumu [1 ]
Umeda, Yuzo [1 ]
Yoshida, Ryuichi [1 ]
Nobuoka, Daisuke [1 ]
Watanabe, Nobuyuki [1 ]
Kuise, Takashi [1 ]
Fuji, Tomokazu [1 ]
Araki, Hiroyuki [1 ]
Fujiwara, Toshiyoshi [1 ]
机构
[1] Okayama Univ, Grad Sch Med Dent & Pharmaceut Sci, Dept Surg Gastroenterol, Okayama 7008558, Japan
关键词
syndrome of inappropriate antidiuretic hormone secretion; SIADH; hyponatremia; liver transplantation; tacrolimus; HYPONATREMIA; TACROLIMUS;
D O I
暂无
中图分类号
R-3 [医学研究方法]; R3 [基础医学];
学科分类号
1001 ;
摘要
Syndrome of inappropriate antidiuretic hormone secretion (SIADH) is an extremely rare cause of hyponatremia post-liver transplantation. A 15-year-old Japanese girl with recurrent cholangitis after Kasai surgery for biliary atresia underwent successful living donor liver transplantation. Peritonitis due to gastrointestinal perforation occurred. Hyponatremia gradually developed but improved after hypertonic sodium treatment. One month later, severe hyponatremia rapidly recurred. We considered the hyponatremia's cause as SIADH. We suspected that tacrolimus was the disease's cause, so we used cyclosporine instead, plus hypertonic sodium plus water intake restriction, which improved the hyponatremia. Symptomatic hyponatremia manifested by SIADH is a rare, serious complication post-liver transplantation.
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页码:85 / 89
页数:5
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