Generating CD8 T Cell Heterogeneity: Attack of the Clones

被引：2

作者：

Marshall, Heather D. ^{[1
]}

Kaech, Susan M. ^{[1
,2
]}

机构：

[1] Yale Univ, Sch Med, Dept Immunobiol, New Haven, CT 06520 USA

[2] Yale Univ, Sch Med, Howard Hughes Med Inst, New Haven, CT 06520 USA

来源：

IMMUNITY | 2013年 / 39卷 / 02期

关键词：

EFFECTOR; DIFFERENTIATION; DIVISION;

D O I：

10.1016/j.immuni.2013.08.008

中图分类号：

R392 [医学免疫学]; Q939.91 [免疫学];

学科分类号：

100102 ;

摘要：

Pathogen-induced inflammation modulates CD8 T cell effector and memory differentiation. In this issue of Immunity, Plumlee et al. (2013) demonstrate that clonally distinct CD8 T cells have the ability to generate numerous types of effector cell fates based on extrinsic pathogen-induced environmental cues.

引用

页码：203 / 205

页数：4

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