disease transmission model;
epidemiology;
control reproduction number;
TRANSMISSION;
AIDS;
D O I:
10.3934/mbe.2009.6.363
中图分类号:
Q [生物科学];
学科分类号:
07 ;
0710 ;
09 ;
摘要:
Since the discovery of HIV/AIDS there have been numerous mathematical models proposed to explain the epidemic of the disease and to evaluate possible control measures. In particular, several recent studied have looked at the potential impact of condom usage on the epidemic [1, 2, 3, 4]. We develop a simple model for HIV/AIDS, and investigate the effectiveness of condoms as possible control strategy. We show that condoms can greatly reduce the number of outbreaks and the size of the epidemic. However, the necessary condom usage levels are much higher than the current estimate. We conclude that condoms alone will not be sufficient to halt the epidemic in most populations unless current estimates of the transmission probabilities are high. Our model has only five independent parameter, which allows for a complete analysis. We show that the assumption of mass action and standard incidence provide similar results, which implies that the result of the simpler mass action model can be used as a good first approximation to the peak of the epidemic.
机构:
Univ Virginia, Biocomplex Inst, Charlottesville, VA 22904 USAUniv Virginia, Biocomplex Inst, Charlottesville, VA 22904 USA
Chen, Jiangzhuo
Espinoza, Baltazar
论文数: 0引用数: 0
h-index: 0
机构:
Univ Virginia, Biocomplex Inst, Charlottesville, VA 22904 USAUniv Virginia, Biocomplex Inst, Charlottesville, VA 22904 USA
Espinoza, Baltazar
Chou, Jingyuan
论文数: 0引用数: 0
h-index: 0
机构:
Univ Virginia, Biocomplex Inst, Charlottesville, VA 22904 USA
Univ Virginia, Dept Comp Sci, Charlottesville, VA USAUniv Virginia, Biocomplex Inst, Charlottesville, VA 22904 USA
Chou, Jingyuan
Gumel, Abba B.
论文数: 0引用数: 0
h-index: 0
机构:
Univ Maryland, Dept Math, College Pk, MD USAUniv Virginia, Biocomplex Inst, Charlottesville, VA 22904 USA
Gumel, Abba B.
Levin, Simon A.
论文数: 0引用数: 0
h-index: 0
机构:
Princeton Univ, Dept Ecol & Evolutionary Biol, Princeton, NJ USAUniv Virginia, Biocomplex Inst, Charlottesville, VA 22904 USA
Levin, Simon A.
Marathe, Madhav
论文数: 0引用数: 0
h-index: 0
机构:
Univ Virginia, Biocomplex Inst, Charlottesville, VA 22904 USA
Univ Virginia, Dept Comp Sci, Charlottesville, VA USAUniv Virginia, Biocomplex Inst, Charlottesville, VA 22904 USA
机构:
School of Mathematics and Physics, The University of Queensland, 4072, QLDSchool of Mathematics and Physics, The University of Queensland, 4072, QLD