One new xanthenone from the marine-derived fungus Aspergillus versicolor MF160003

被引:8
作者
Song, Zhijun [1 ,2 ]
Gao, Jieyu [1 ,3 ]
Hu, Jiansen [1 ,2 ]
He, Hongtao [1 ,2 ]
Huang, Pei [1 ,4 ]
Zhang, Lixin [5 ]
Song, Fuhang [1 ]
机构
[1] Chinese Acad Sci, Inst Microbiol, Key Lab Pathogen Microbiol & Immunol, Beijing, Peoples R China
[2] Univ Chinese Acad Sci, Beijing, Peoples R China
[3] Hefei Univ Technol, Sch Food & Biol Engn, Hefei, Anhui, Peoples R China
[4] Zunyi Med Univ, Affiliated Hosp, Dept Pediat, Zunyi, Peoples R China
[5] East China Univ Sci Technol, State Key Lab Bioreactor Enng, Shanghai, Peoples R China
基金
中国国家自然科学基金; 国家重点研发计划;
关键词
Marine-derived fungus; Aspergillus versicolor; xanthenone; anti-BCG; NATURAL-PRODUCTS; POLYKETIDES; DRUGS;
D O I
10.1080/14786419.2019.1597355
中图分类号
O69 [应用化学];
学科分类号
081704 ;
摘要
A new xanthenone derivative, 3-hydroxy pinselin (1), together with five known analogues (2-6) were isolated from the marine-derived fungus Aspergillus versicolor MF160003. Their structures were identified by extensive 1D- and 2D-NMR, and high-resolution mass spectrometry data. Compounds 5 and 6 showed moderate bioactivities against BCG with MIC values of 40 and 20 mu g/mL, respectively.
引用
收藏
页码:2907 / 2912
页数:6
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