One new xanthenone from the marine-derived fungus Aspergillus versicolor MF160003

被引：8

作者：

Song, Zhijun ^{[1
,2
]}

Gao, Jieyu ^{[1
,3
]}

Hu, Jiansen ^{[1
,2
]}

He, Hongtao ^{[1
,2
]}

Huang, Pei ^{[1
,4
]}

Zhang, Lixin ^{[5
]}

Song, Fuhang ^{[1
]}

机构：

[1] Chinese Acad Sci, Inst Microbiol, Key Lab Pathogen Microbiol & Immunol, Beijing, Peoples R China

[2] Univ Chinese Acad Sci, Beijing, Peoples R China

[3] Hefei Univ Technol, Sch Food & Biol Engn, Hefei, Anhui, Peoples R China

[4] Zunyi Med Univ, Affiliated Hosp, Dept Pediat, Zunyi, Peoples R China

[5] East China Univ Sci Technol, State Key Lab Bioreactor Enng, Shanghai, Peoples R China

来源：

NATURAL PRODUCT RESEARCH | 2020年 / 34卷 / 20期

基金：

中国国家自然科学基金; 国家重点研发计划;

关键词：

Marine-derived fungus; Aspergillus versicolor; xanthenone; anti-BCG; NATURAL-PRODUCTS; POLYKETIDES; DRUGS;

D O I：

10.1080/14786419.2019.1597355

中图分类号：

O69 [应用化学];

学科分类号：

081704 ;

摘要：

A new xanthenone derivative, 3-hydroxy pinselin (1), together with five known analogues (2-6) were isolated from the marine-derived fungus Aspergillus versicolor MF160003. Their structures were identified by extensive 1D- and 2D-NMR, and high-resolution mass spectrometry data. Compounds 5 and 6 showed moderate bioactivities against BCG with MIC values of 40 and 20 mu g/mL, respectively.

引用

页码：2907 / 2912

页数：6

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