The Children's Oncology Group Radiation Oncology Discipline: 15 Years of Contributions to the Treatment of Childhood Cancer

被引：33

作者：

Breneman, John C. ^{[1
]}

Donaldson, Sarah S. ^{[2
]}

Constine, Louis ^{[3
,4
]}

Merchant, Thomas ^{[5
]}

Marcus, Karen ^{[6
]}

Paulino, Arnold C. ^{[7
]}

Followill, David ^{[8
]}

Mahajan, Anita ^{[9
]}

Laack, Nadia ^{[9
]}

Esiashvili, Natia ^{[10
]}

Haas-Kogan, Daphne ^{[6
]}

Laurie, Fran ^{[11
]}

Olch, Arthur ^{[12
,13
]}

Ulin, Kenneth ^{[11
,14
]}

Hodgson, David ^{[15
,16
]}

Yock, Torunn I. ^{[17
]}

Terezakis, Stephanie ^{[18
]}

Krasin, Matt ^{[5
]}

Panoff, Joseph ^{[19
]}

Chuba, Paul ^{[20
]}

Hua, Chia-Ho ^{[5
]}

Hess, Clayton B. ^{[17
]}

Houghton, Peter J. ^{[21
]}

Wolden, Suzanne ^{[22
]}

Buchsbaum, Jeff ^{[23
]}

Fitzgerald, Thomas J. ^{[11
]}

Kalapurakal, John A. ^{[24
]}

机构：

[1] Univ Cincinnati, Dept Radiat Oncol, Cincinnati, OH USA

[2] Stanford Univ, Dept Radiat Oncol, Sch Med, Stanford, CA 94305 USA

[3] Univ Rochester, Med Ctr, Dept Radiat Oncol, Rochester, NY 14642 USA

[4] Univ Rochester, Med Ctr, Dept Pediat, Rochester, NY 14642 USA

[5] St Jude Childrens Res Hosp, Dept Radiat Oncol, 332 N Lauderdale St, Memphis, TN 38105 USA

[6] Harvard Med Sch, Boston Childrens Hosp, Dept Radiat Oncol, Brigham & Womens Hosp,Dana Farber Canc Inst, Boston, MA USA

[7] Univ Texas MD Anderson Canc Ctr, Dept Radiat Oncol, Houston, TX 77030 USA

[8] Univ Texas MD Anderson Canc Ctr, Houston Qual Assurance Ctr, Imaging & Radiat Oncol Core IROC, Houston, TX 77030 USA

[9] Mayo Clin, Dept Radiat Oncol, Rochester, MN USA

[10] Emory Univ, Dept Radiat Oncol, Winship Canc Inst, Atlanta, GA 30322 USA

[11] Imaging & Radiat Oncol Core IROC Rhode Isl, Lincoln, RI USA

[12] Univ Southern Calif, Keck Sch Med, Radiat Oncol Program, Los Angeles, CA USA

[13] Childrens Hosp Los Angeles, Los Angeles, CA 90027 USA

[14] Univ Massachusetts, Boston, MA 02125 USA

[15] Princess Margaret Canc Ctr, Radiat Med Program, Toronto, ON, Canada

[16] Pediat Oncol Grp Ontario, Toronto, ON, Canada

[17] Harvard Med Sch, Massachusetts Gen Hosp, Dept Radiat Oncol, Boston, MA USA

[18] Johns Hopkins Univ, Dept Radiat Oncol, Baltimore, MD USA

[19] 21st Century Oncol, Key West, FL USA

[20] St John Hosp & Med Ctr, Dept Radiat Oncol, Detroit, MI USA

[21] Univ Texas Hlth Sci Ctr San Antonio, Greehey Childrens Canc Res Inst, San Antonio, TX 78229 USA

[22] Mem Sloan Kettering, Dept Radiat Oncol, New York, NY USA

[23] NCI, Bethesda, MD 20892 USA

[24] Northwestern Univ, Dept Radiat Oncol, Feinberg Sch Med, Chicago, IL 60611 USA

来源：

INTERNATIONAL JOURNAL OF RADIATION ONCOLOGY BIOLOGY PHYSICS | 2018年 / 101卷 / 04期

基金：

美国国家卫生研究院;

关键词：

ACUTE LYMPHOBLASTIC-LEUKEMIA; INTERMEDIATE-RISK RHABDOMYOSARCOMA; TISSUE SARCOMA COMMITTEE; GROUP-III RHABDOMYOSARCOMA; LOCALIZED EWING SARCOMA; INTERGROUP RHABDOMYOSARCOMA; WILMS-TUMOR; HODGKIN LYMPHOMA; CRANIOSPINAL IRRADIATION; PHASE-III;

D O I：

10.1016/j.ijrobp.2018.03.002

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

Purpose: Our aim was to review the advances in radiation therapy for the management of pediatric cancers made by the Children's Oncology Group (COG) radiation oncology discipline since its inception in 2000. Methods and Materials: The various radiation oncology disease site leaders reviewed the contributions and advances in pediatric oncology made through the work of the COG. They have presented outcomes of relevant studies and summarized current treatment policies developed by consensus from experts in the field. Results: The indications and techniques for pediatric radiation therapy have evolved considerably over the years for virtually all pediatric tumor types, resulting in improved cure rates together with the potential for decreased treatment-related morbidity and mortality. Conclusions: The COG radiation oncology discipline has made significant contributions toward the treatment of childhood cancer. Our discipline is committed to continuing research to refine and modernize the use of radiation therapy in current and future protocols with the goal of further improving the cure rates and quality of life of children with cancer. © 2018 Elsevier Inc.

引用

页码：860 / 874

页数：15

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