Effects of micropore porosifer on the formation of bone-like apatite in the calcium phosphate ceramics

The formation of the bone-like apatite containing carbonate in the calcium phosphate ceramics is important to the growth of the new bone and the osteoinductivity of the materials. The effect of the micropore porosifer on the formation of the bone-like apatite in carbonate-contained HA/beta-TCP ceramics prepared by the new technique was discussed in detail for the first time. The results show that the bone-like apatite can be formed in shorter time (about 6 days) in this ceramics for the carbonate mixing into the structure of the apatite crystal. The results also show that the ceramics with the PVB micropore porosifer lead to the better bone-like apatite formation compared with the SA micropore porosifer, and the best ratio is M-calcium phosphate powder:M-PVB=1:0.3. The optimization of the micropore porosifer is good to improving the osteoinductivity of the carbonate-contained HA/beta-TCP ceramics, which is great help to the restoration of the bone defect.