Impact of ovarian endometrioma on assisted reproduction outcomes

被引：181
作者：
Gupta, Sajal
Agarwall, Ashok
Agarwal, Rishi
Ricardo Loret de Mola, J.
机构：
[1] Cleveland Clin Fdn, Glickman Urol Inst, Ctr Res Reprod, Cleveland, OH 44195 USA
[2] Cleveland Clin Fdn, Dept Obstet Gynecol, Cleveland, OH 44195 USA
[3] Univ Hosp, MacDonald Womens Hosp, Dept Obstet & Gynecol, Div Reprod Endocrinol & Infertil, Cleveland, OH USA
来源：
REPRODUCTIVE BIOMEDICINE ONLINE | 2006年 / 13卷 / 03期
关键词：
embryo quality; in-vitro fertilization; intracytoplasmic sperm injection; ovarian endometrioma; retrieved oocytes;
D O I：
10.1016/S1472-6483(10)61439-3
中图分类号：
R71 [妇产科学];
学科分类号：
100211 ;
摘要：
The effects of ovarian endometrioma on fertility outcomes with IVF and embryo transfer have been causally related to poor outcomes. The objective of this meta-analysis was to evaluate the ovarian reserve and ovarian responsiveness to ovarian stimulation and assisted reproduction outcomes in patients with ovarian endometrioma. The odds for clinical pregnancy were not affected significantly in patients with ovarian endometrioma compared with controls, with an overall odds ratio of 1.07 from three studies [95% CI: (0.63, 1.81), P = 0.79]. The overall pregnancy rate was similar with an estimated odds ratio of 1.17 [95% CI: (0.85, 1.60), P = 0.34]. Decreased ovarian responsiveness to ovarian stimulation in patients with ovarian endometrioma may be due to a reduced number of follicles in these patients compared with controls (P = 0.002). Prospective randomized controlled trials are needed to assess whether surgical treatment versus no surgical treatment improves pregnancy outcomes in patients with ovarian endometrioma undergoing assisted reproduction cycles.
引用
收藏
页码：349 / 360
页数：12
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