A general model of non-communicable diseases and its qualitative analysis without finding the eigenvalues

被引:1
作者
Daud, Auni Aslah Mat [1 ]
Qing, Toh Cher [1 ]
机构
[1] Univ Malaysia Terengganu, Fac Ocean Engn Technol & Informat, Kuala Nerus 21030, Malaysia
来源
JOURNAL OF MATHEMATICS AND COMPUTER SCIENCE-JMCS | 2022年 / 24卷 / 01期
关键词
Mathematical modelling; qualitative analysis; non-communicable disease; venous thromboembolism; global stability; compartmental analysis; VENOUS THROMBOEMBOLISM; PREGNANCY; RISK;
D O I
10.22436/jmcs.024.01.07
中图分类号
O1 [数学];
学科分类号
0701 ; 070101 ;
摘要
Obtaining the analytical solutions of a linear ordinary differential equations is impossible without finding the eigenvalues. In this study, a general linear model of non-communicable disease (NCD) is formulated using the compartmental analysis and its qualitative properties are analyzed without finding the eigenvalues. NCDs are diseases which are not passed from person to person. The proof of the qualitative properties of the general model including the existence and uniqueness of its solution and equilibrium, and the positivity and boundedness of its solutions are provided. The global stability of the general model is analyzed using the theorem of compartmental matrix and Lyapunov function. It is found that the model has one unique non-negative equilibrium which is globally exponentially stable. As a real-world example, the general model and its qualitative analysis are implemented to a NCD, namely venous thromboembolism (VTE) among pregnant and postpartum women. VTE is selected in this study as it is a major global health burden due to its association with disability and lower quality of life and death.
引用
收藏
页码:73 / 81
页数:9
相关论文
共 19 条
  • [1] Anderson DH, 1983, Compartmental modeling and tracer kinetics
  • [2] A mathematical model for the burden of diabetes and its complications
    Boutayeb, A.
    Twizell, E. H.
    Achouayb, K.
    Chetouani, A.
    [J]. BIOMEDICAL ENGINEERING ONLINE, 2004, 3 (1)
  • [3] Brauer F., 1969, QUALITATIVE THEORY O, P1
  • [4] Development and Analysis of a Mathematical Model for the Population Dynamics of Diabetes Mellitus During Pregnancy
    Auni Aslah Mat Daud
    Toh C.Q.
    Saidun S.
    [J]. Mathematical Models and Computer Simulations, 2020, 12 (4) : 620 - 630
  • [5] Daud A. A. Mat, 2018, SPRINGER P MATH STAT, V295, P3
  • [6] Daud AAM, 2020, INT J MATH COMPUT SC, V15, P501
  • [7] A mathematical model to study the population dynamics of hypertensive disorders during pregnancy
    Daud, Auni Aslah Mat
    Toh, Cher Qing
    Saidur, Salilah
    [J]. JOURNAL OF INTERDISCIPLINARY MATHEMATICS, 2019, 22 (04) : 433 - 450
  • [8] Thromboembolism
    Drife, J
    [J]. BRITISH MEDICAL BULLETIN, 2003, 67 : 177 - 190
  • [9] Engel K. J., 2000, One-Parameter Semigroups for Linear Evolution Equations, V194
  • [10] An introduction to mathematical models in sexually transmitted disease epidemiology
    Garnett, GP
    [J]. SEXUALLY TRANSMITTED INFECTIONS, 2002, 78 (01) : 7 - 12