Chiasmal glioma in neurofibromatosis type 1 with severe visual loss regained with radiation

Children with neurofibromatosis type 1 (NFI) and chiasmal gliomas are often considered unlikely to experience progressive visual loss, However, this may not be true, We report a 5-year, 6-month-old boy, with recently diagnosed NF1, who had a chiasmal glioma diagnosed after neuroimaging. He subsequently experienced rapid visual acuity loss, His vision improved significantly after irradiation, The controversy surrounding radiotherapy for chiasmal glioma is discussed, (C) 1997 by Elsevier Science Inc, All rights reserved.