Detrimental role of humoral signalling in cardio-renal cross-talk

被引：2
|
作者：
Cantaluppi, Vincenzo [1 ]
Dellepiane, Sergio [1 ]
Quercia, Alessandro D. [1 ]
Ferrario, Silvia [1 ]
机构：
[1] Univ Turin, Nephrol Dialysis & Kidney Transplantat Unit, Dept Med Sci, Azienda Osped Citta Salute & Sci Molinette, I-10126 Turin, Italy
来源：
CRITICAL CARE | 2014年 / 18卷 / 01期
关键词：
BOUND UREMIC TOXINS; RENAL-FAILURE; DYSFUNCTION; KIDNEY; INJURY; TARGET;
D O I：
10.1186/cc13704
中图分类号：
R4 [临床医学];
学科分类号：
1002 ; 100602 ;
摘要：
In critically ill patients, any acute organ injury is associated with a sudden change of circulating factors that may play a role in distant organ dysfunction through a complex cross-talk. In this issue, Virzi and colleagues discuss the relevance of humoral signalling between heart and kidney, focusing on type 1 and type 3 cardio renal syndrome. We herein review the mechanisms of heart-kidney cross-talk, discussing the role of circulating detrimental mediators in the pathogenetic mechanisms of cardio-renal syndrome.
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页数：2
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