Evaluation of physical, mechanical, and biodegradation of chitosan/graphene oxide composite as bone substitutes

In this study, a nanocomposite was prepared from chitosan (Cs) and graphene oxide (GO) with different percentages. The results of Fourier-transform infrared spectroscopy, thermal gravity analysis, and X-ray diffraction showed that the presence of GO nanoparticles increased thermal stability and crystallinity of Cs. Tensile test results showed that the presence of 0.3 wt.% GO in Cs film increased the tensile strength and Young's modulus by 296% and 193%, respectively. The results of bioactivity and biodegradation test showed that the presence of GO in Cs film increased the density of the apatite-like layer on the surface and the degradation time. [GRAPHICS] .