Among the regions always existed the differences, they dispose of various raw materials, natural resources and diverse human potential. Within the regional policy in states of EU, and in Czech Republic the government tries to reduce the disparities of regions so as to attend in each region to balanced socioeconomic growth and to increase their competitiveness. The competitiveness of the region we could understand as the region with prospering business and innovative environment and with functional market (science and research). Influence of technological development causes that knowledge potential of population, i.e. enough qualified workforce together with innovations is coming to forefront and is supplying another factors (for example the localization factors). The importance of analysis of knowledge structure results from considerable influence of education for the competitiveness and for development of region, when inadequately qualified population could have the negative influence on development of the business environment, it comes to following stagnation of economics development and following the loss of competitiveness. Within the paper will be search structure of populations education in work market in Moravian-Silesian Region and then to compare with level of education in other regions in Czech Republic. In the end will be predict the progress of knowledge groups in MSR, which could to take measures for the increase of education of population in region.
