Guidelines for treating iron overload in myelodysplastic syndromes: a Taiwan consensus statement

被引:6
作者
Ko, Bor-Sheng [1 ,2 ]
Chang, Cheng-Shyong [3 ]
Chang, Ming-Chih [4 ]
Chen, Tsai Yun [5 ]
Chiou, Tzeon-Jye [6 ]
Chiu, Chang-Fang [7 ,8 ]
Huang, Wen-Li [9 ]
Kao, Woei-Yau [10 ]
Lan, Yii-Jenq [11 ]
Lin, Shen-Fung [12 ,13 ]
Tan, Tran-Der [14 ]
Tang, Jih-Luh [1 ]
Tzeng, Cheng-Hwai [15 ]
Wang, Po-Nan [16 ]
Yet, Su-Pen [8 ]
Tien, Hwei-Fang [1 ]
机构
[1] Natl Taiwan Univ Hosp, Dept Internal Med, Div Hematol, Taipei 100, Taiwan
[2] Natl Hlth Res Inst, Inst System & Cellular Med, Miaoli, Taiwan
[3] Changhua Christian Hosp, Dept Internal Med, Changhua, Taiwan
[4] Mackay Mem Hosp, Mackay Med Coll, Dept Hematol Oncol, Taipei, Taiwan
[5] Natl Cheng Kung Univ, Coll Med, Dept Internal Med, Sect Hematol Oncol, Tainan 70101, Taiwan
[6] Natl Yang Ming Univ, Sch Med, Taipei Vet Gen Hosp, Div Transfus Med,Dept Med, Taipei 112, Taiwan
[7] China Med Univ Hosp, Ctr Canc, Taichung, Taiwan
[8] China Med Univ, Sch Med, Dept Med, Taichung, Taiwan
[9] Taichung Vet Gen Hosp, Div Hematol Oncol, Taipei, Taiwan
[10] Buddhist Tzu Chi Gen Hosp, Taipei Branch, Dept Internal Med, Div Hematol Oncol, New Taipei City, Taiwan
[11] Chang Gung Mem Hosp Keelung, Dept Internal Med, Div Hematol Oncol, Keelung, Taiwan
[12] Kaohsiung Med Univ, Div Hematol Oncol, Dept Internal Med, Kaohsiung, Taiwan
[13] Kaohsiung Med Univ, Dept Internal Med, Coll Med, Kaohsiung, Taiwan
[14] Koo Fdn, Sun Yat Sen Canc Ctr, Taipei, Taiwan
[15] Natl Yang Ming Univ, Sch Med, Taipei Vet Gen Hosp, Div Hematol Oncol,Dept Med, Taipei 112, Taiwan
[16] Chang Gung Mem Hosp Linkou, Dept Internal Med, Div Hematol Oncol, Taoyuan, Taiwan
关键词
Guidelines; Taiwan; MDS; ICT; Iron overload; Ferritin; PRETRANSPLANTATION SERUM FERRITIN; CHELATION-THERAPY; NONRELAPSE MORTALITY; THALASSEMIA MAJOR; INFERIOR SURVIVAL; PROGNOSTIC IMPACT; MDS PATIENTS; DEFERASIROX; HEMATOPOIESIS; COMPLICATIONS;
D O I
10.1007/s12185-014-1607-x
中图分类号
R5 [内科学];
学科分类号
1002 ; 100201 ;
摘要
Iron overload is common in myelodysplastic syndrome (MDS) patients, and an accumulation of evidence shows that iron chelation may have benefits in these patients. However, discussion and consensus about iron chelation therapy (ICT) for MDS patients is lacking in Taiwan and other Southeast Asian countries. An Expert Panel in Taiwan was organized in 2011 to develop iron overload guidelines and provide a uniform reference for physicians treating MDS patients with iron overload, with specific regard to when to initiate ICT, in which patients, and the clinical and scientific rationale behind its use.
引用
收藏
页码:7 / 15
页数:9
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