e19a2 BCR-ABL fusion transcript in typical chronic myeloid leukaemia: a report of two cases

被引：17
|
作者：
Mondal, B. C.
Majumdar, S.
Dasgupta, U. B.
Chaudhuri, U.
Chakrabarti, P.
Bhattacharyya, S.
机构：
[1] Univ Calcutta, Dept Biophys Mol Biol & Genet, Kolkata 700009, W Bengal, India
[2] Inst Haematol & Transfus Med, Kolkata, W Bengal, India
来源：
JOURNAL OF CLINICAL PATHOLOGY | 2006年 / 59卷 / 10期
关键词：
D O I：
10.1136/jcp.2005.029595
中图分类号：
R36 [病理学];
学科分类号：
100104 ;
摘要：
This report describes two patients with chronic myeloid leukaemia (CML): one of them developed accelerated phase CML and died 8 years after diagnosis and the other is at the chronic phase. Sequence analysis of reverse transcription-polymerase chain reaction products showed the presence of BCR-ABL fusion transcript e19a2. This finding suggests that CML carrying mu-BCR breakpoint may exhibit a clinical course similar to typical CML.
引用
收藏
页码：1102 / 1103
页数：2
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