CMY-13, a novel inducible cephalosporinase encoded by an Escherichia coli plasmid

被引：44

作者：

Miriagou, V

Tzouvelekis, LS

Villa, L

Lebessi, E

Vatopoulos, AC

Carattoli, A

Tzelepi, E

机构：

[1] Hellenic Pasteur Inst, Bacteriol Lab, Athens 11527, Greece

[2] Univ Athens, Sch Med, Dept Microbiol, Athens, Greece

[3] Natl Sch Publ Hlth, Div Microbiol, Athens, Greece

[4] Ist Super Sanita, Dept Infect Dis, I-00161 Rome, Italy

来源：

ANTIMICROBIAL AGENTS AND CHEMOTHERAPY | 2004年 / 48卷 / 08期

关键词：

D O I：

10.1128/AAC.48.8.3172-3174.2004

中图分类号：

Q93 [微生物学];

学科分类号：

071005 ; 100705 ;

摘要：

An IncN plasmid (p541) from Escherichia coli carried a Citrobacter freundii-derived sequence of 4,252 bp which included an ampC-ampR region and was bound by two directly repeated IS26 elements. ampC encoded a novel cephalosporinase (CMY-13) with activity similar to that of CMY-2. AmpR was likely functional as indicated in induction experiments.

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页码：3172 / 3174

页数：3

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