Hits and Misses in Targeting Pediatric Cancers

被引：1

作者：

Bernstein, Mark L. ^{[1
]}

机构：

[1] Dalhousie Univ, Dept Pediat, IWK Hlth Ctr, Div Hematol Oncol, Halifax, NS B3K 6R8, Canada

来源：

PEDIATRIC BLOOD & CANCER | 2009年 / 52卷 / 07期

关键词：

GASTROINTESTINAL STROMAL TUMORS; IMATINIB MESYLATE; EWINGS-SARCOMA; PHASE-II; KIT; TRIAL;

D O I：

10.1002/pbc.21937

中图分类号：

R73 [肿瘤学];

学科分类号：

100214 ;

摘要：

引用

页码：751 / 752

页数：2

共 16 条

[1] Long-term results from a randomized phase II trial of standard- versus higher-dose imatinib mesylate for patients with unresectable or metastatic gastrointestinal stromal tumors expressing KIT [J].

Blanke, Charles D. ;

Demetri, George D. ;

von Mehren, Margaret ;

Heinrich, Michael C. ;

Eisenberg, Burton ;

Fletcher, Jonathan A. ;

Corless, Christopher L. ;

Fletcher, Christopher D. M. ;

Roberts, Peter J. ;

Heinz, Daniela ;

Wehre, Elisabeth ;

Nikolova, Zariana ;

Joensuu, Heikki .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (04) :620-625

[2] Phase III randomized, intergroup trial assessing imatinib mesylate at two dose levels in patients with unresectable or metastatic gastrointestinal stromal tumors expressing the kit receptor tyrosine kinase: S0033 [J].

Blanke, Charles D. ;

Rankin, Cathryn ;

Demetri, George D. ;

Ryan, Christopher W. ;

von Mehren, Margaret ;

Benjamin, Robert S. ;

Raymond, A. Kevin ;

Bramwell, Vivien H. C. ;

Baker, Laurence H. ;

Maki, Robert G. ;

Tanaka, Michael ;

Hecht, J. Randolph ;

Heinrich, Michael C. ;

Fletcher, Christopher D. M. ;

Crowley, John J. ;

Borden, Ernest C. .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (04) :626-632

[3] A phase II study of imatinib mesylate in children with refractory or relapsed solid tumors: A children's oncology group study [J].

Bond, Mason ;

Bernstein, Mark L. ;

Pappo, Alberto ;

Schultz, Kirk R. ;

Krailo, Mark ;

Blaney, Susan M. ;

Adamson, Peter C. .

PEDIATRIC BLOOD & CANCER, 2008, 50 (02) :254-258

[4] Imatinib in children with newly diagnosed chronic phase chronic myelogenous leukemia (CP CML): AAML0123 COG study. [J].

Champagne, Martin A. ;

Fu, Cecilia ;

Chang, Myron ;

Cooley, Linda ;

Heerema, Nyla A. ;

Wood, Charlotte ;

French, Mary Ellen ;

Smith, Franklin O. ;

Bernstein, Mark L. .

BLOOD, 2006, 108 (11) :607A-607A

[5]

Druker BJ, 2002, J NATL CANCER I, V94, P1660

[6] Correlation of Kinase Genotype and Clinical Outcome in the North American Intergroup Phase III Trial of Imatinib Mesylate for Treatment of Advanced Gastrointestinal Stromal Tumor: CALGB 150105 Study by Cancer and Leukemia Group B and Southwest Oncology Group [J].

Heinrich, Michael C. ;

Owzar, Kouros ;

Corless, Christopher L. ;

Hollis, Donna ;

Borden, Ernest C. ;

Fletcher, Christopher D. M. ;

Ryan, Christopher W. ;

von Mehren, Margaret ;

Blanke, Charles D. ;

Rankin, Cathryn ;

Benjamin, Robert S. ;

Bramwell, Vivien H. ;

Demetri, George D. ;

Bertagnolli, Monica M. ;

Fletcher, Jonathan A. .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (33) :5360-5367

[7] Primary and Secondary Kinase Genotypes Correlate With the Biological and Clinical Activity of Sunitinib in Imatinib-Resistant Gastrointestinal Stromal Tumor [J].

Heinrich, Michael C. ;

Maki, Robert G. ;

Corless, Christopher L. ;

Antonescu, Cristina R. ;

Harlow, Amy ;

Griffith, Diana ;

Town, Ajia ;

McKinley, Arin ;

Ou, Wen-Bin ;

Fletcher, Jonathan A. ;

Fletcher, Christopher D. M. ;

Huang, Xin ;

Cohen, Darrel P. ;

Baum, Charles M. ;

Demetri, George D. .

JOURNAL OF CLINICAL ONCOLOGY, 2008, 26 (33) :5352-5359

[8]

JANEWAY K, PEDIAT BLOO IN PRESS

[9] Pediatric KIT-wild-type and platelet-derived growth factor receptor α-wild-type gastrointestinal stromal tumors share KIT activation but not mechanisms of genetic progression with adult gastrointestinal stromal tumors [J].

Janeway, Katherine A. ;

Liegl, Bernadette ;

Harlow, Amy ;

Le, Claudia ;

Perez-Atayde, Antonio ;

Kozakewich, Harry ;

Corless, Christopher L. ;

Heinrich, Nflchael C. ;

Fletcher, Jonathan A. .

CANCER RESEARCH, 2007, 67 (19) :9084-9088

[10] Chronic myeloid leukaemia: the evolution of gene-targeted therapy [J].

Joske, David J. L. .

MEDICAL JOURNAL OF AUSTRALIA, 2008, 189 (05) :277-282

← 1 2 →