Prospective Epidemiological Research Studies in Iran (the PERSIAN Cohort Study): Rationale, Objectives, and Design

被引：473

作者：

Poustchi, Hossein ^{[1
]}

Eghtesad, Sareh ^{[1
]}

Kamangar, Farin ^{[2
,3
]}

Etemadi, Arash ^{[4
]}

Keshtkar, Abbas-Ali ^{[5
]}

Hekmatdoost, Azita ^{[6
]}

Mohammadi, Zahra ^{[1
]}

Mahmoudi, Zahra ^{[1
]}

Shayanrad, Amaneh ^{[1
]}

Roozafzai, Farzin ^{[1
]}

Sheikh, Mahdi ^{[1
]}

Jalaeikhoo, Alireza ^{[1
]}

Somi, Mohammad Hossein ^{[7
]}

Mansour-Ghanaei, Fariborz ^{[8
]}

Najafi, Farid ^{[9
]}

Bahramali, Ehsan ^{[10
]}

Mehrparvar, Amirhoushang

Ansari-Moghaddam, Alireza ^{[11
]}

Enayati, Ahmad Ali ^{[12
,13
]}

Nadimi, Ali Esmaeili ^{[14
]}

Rezaianzadeh, Abbas ^{[15
]}

Saki, Nader ^{[16
]}

Alipour, Fatemeh ^{[17
]}

Kelishadi, Roya ^{[18
]}

Rahimi-Movaghar, Afarin ^{[19
]}

Aminisani, Nayyereh ^{[20
]}

Boffetta, Paolo ^{[21
]}

Malekzadeh, Reza ^{[3
]}

机构：

[1] Tehran Univ Med Sci UMS, Digest Dis Res Inst, Liver & Pancreatobiliary Dis Res Ctr, Tehran, Iran

[2] Morgan State Univ, Sch Comp Math & Nat Sci, Dept Biol, Baltimore, MD 21239 USA

[3] Tehran UMS, Digest Dis Res Inst, Digest Oncol Res Ctr, Tehran, Iran

[4] NCI, Div Canc Epidemiol & Genet, Bethesda, MD 20892 USA

[5] Tehran UMS, Sch Publ Hlth, Dept Hlth Sci Educ Dev, Tehran, Iran

[6] Shahid Beheshti UMS, Sch Nutrit Sci & Dietet, Dept Clin Nutr, Tehran, Iran

[7] Tabriz UMS, Liver & Gastrointestinal Dis Res Ctr, Tabriz, Iran

[8] Guilan UMS, Gastrointestinal & Liver Dis Res Ctr, Dept Gastroenterol, Rasht, Iran

[9] Kermanshah UMS, Sch Publ Hlth, Res Ctr Environm Determinants Hlth, Kermanshah, Iran

[10] Fasa UMS, Noncommunicable Dis Res Ctr, Fasa, Iran

[11] Zahedan UMS, Hlth Promot Res Ctr, Zahedan, Iran

[12] Mazandaran UMS, Sch Publ Hlth, Sari, Iran

[13] Mazandaran UMS, Hlth Sci Res Ctr, Sari, Iran

[14] Rafsanjan UMS, Sch Med, Dept Cardiol, Rafsanjan, Iran

[15] Shiraz UMS, Sch Hlth, Dept Epidemiol, Shiraz, Iran

[16] Ahvaz JundishapurUMS, Hearing & Speech Res Ctr, Dept Otolaryngol Head & Neck Surg, Ahvaz, Iran

[17] TehranUMS, Farabi Eye Hosp, Eye Res Ctr, Tehran, Iran

[18] Isfahan UMS, Res Inst Primordial Prevent Non Communicable Dis, Child Growth & Dev Res Ctr, Dept Pediat, Esfahan, Iran

[19] Tehran UMS, Iranian Natl Ctr Addict Studies, Tehran, Iran

[20] Tabriz UMS, Fac Hlth Sci, Dept Stat & Epidemiol, Tabriz, Iran

[21] Icahn Sch Med Mt Sinai, Dept Oncol Sci, New York, NY 10029 USA

来源：

AMERICAN JOURNAL OF EPIDEMIOLOGY | 2018年 / 187卷 / 04期

关键词：

cohort studies; Iran; noncommunicable diseases; Prospective Epidemiological Research Studies in Iran (PERSIAN); SQUAMOUS-CELL CARCINOMA; CANCER; RISK; ASSOCIATION; MORTALITY; OPIUM;

D O I：

10.1093/aje/kwx314

中图分类号：

R1 [预防医学、卫生学];

学科分类号：

1004 ; 120402 ;

摘要：

Noncommunicable diseases (NCDs) account for 76% of deaths in Iran, and this number is on the rise, in parallel with global rates. Many risk factors associated with NCDs are preventable; however, it is first necessary to conduct observational studies to identify relevant risk factors and the most appropriate approach to controlling them. Iran is a multiethnic country; therefore, in 2014 the Ministry of Health and Medical Education launched a nationwide cohort study-Prospective Epidemiological Research Studies in Iran (PERSIAN)-in order to identify the most prevalent NCDs among Iran's ethnic groups and to investigate effective methods of prevention. The PERSIAN study consists of 4 population-based cohorts; the adult component (the PERSIAN Cohort Study), described in this article, is a prospective cohort study including 180,000 persons aged 35-70 years from 18 distinct areas of Iran. Upon joining the cohort, participants respond to interviewer-administered questionnaires. Blood, urine, hair, and nail samples are collected and stored. To ensure consistency, centrally purchased equipment is sent to all sites, and the same team trains all personnel. Routine visits and quality assurance/control measures are taken to ensure protocol adherence. Participants are followed for 15 years postenrollment. The PERSIAN study is currently in the enrollment phase; cohort profiles will soon emerge.

引用

页码：647 / 655

页数：9

共 26 条

[1]

[Anonymous], 1987, STAT METHODS CANC RE

[2]

[Anonymous], 2014, World Health Organization Technical Report Series 985

[3] NURSES HEALTH STUDY [J].

BELANGER, CF ;

HENNEKENS, CH ;

ROSNER, B ;

SPEIZER, FE .

AMERICAN JOURNAL OF NURSING, 1978, 78 (06) :1039-1040

[4]

Centers for Disease Control and Prevention (CDC) National Center for Health Statistics (NCHS), 2007, NAT HLTH NUTR EXAM S

[5]

Esmaeimzadeh N, 2015, HORMOZGAN MED J, V19, P74

[6] Hazards of cigarettes, smokeless tobacco and waterpipe in a Middle Eastern Population: a Cohort Study of 50 000 individuals from Iran [J].

Etemadi, Arash ;

Khademi, Hooman ;

Kamangar, Farin ;

Freedman, Neal D. ;

Abnet, Christian C. ;

Brennan, Paul ;

Malekzadeh, Reza .

TOBACCO CONTROL, 2017, 26 (06) :674-682

[7] Mortality and cancer in relation to ABO blood group phenotypes in the Golestan Cohort Study [J].

Etemadi, Arash ;

Kamangar, Farin ;

Islami, Farhad ;

Poustchi, Hossein ;

Pourshams, Akram ;

Brennan, Paul ;

Boffetta, Paolo ;

Malekzadeh, Reza ;

Dawsey, Sanford M. ;

Abnet, Christian C. ;

Emadi, Ashkan .

BMC MEDICINE, 2015, 13

[8]

Institute for Health Metrics and Evaluation, 2010, GBD PROF IR GLOB BUR

[9]

International Agency for Research on Cancer, EPIC STUD

[10] Tea drinking habits and oesophageal cancer in a high risk area in northern Iran: population based case-control study [J].

Islami, Farhad ;

Pourshams, Akram ;

Nasrollahzadeh, Dariush ;

Kamangar, Farin ;

Fahimi, Saman ;

Shakeri, Ramin ;

Abedi-Ardekani, Behnoush ;

Merat, Shahin ;

Vahedi, Homayoon ;

Semnani, Shahryar ;

Abnet, Christian C. ;

Brennan, Paul ;

Moller, Henrik ;

Saidi, Farrokh ;

Dawsey, Sanford M. ;

Malekzadeh, Reza ;

Boffetta, Paolo .

BMJ-BRITISH MEDICAL JOURNAL, 2009, 338 :876-879

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