Duplex Stabilization and Energy Transfer in Zipper Porphyrin-DNA

被引:92
|
作者
Nguyen, ThaoNguyen [1 ]
Brewer, Ashley [1 ]
Stulz, Eugen [1 ]
机构
[1] Univ Southampton, Sch Chem, Southampton SO17 1BJ, Hants, England
基金
英国工程与自然科学研究理事会;
关键词
DNA; energy transfer; helical structures; metalation; porphyrinoids; NUCLEIC-ACID; SUPRAMOLECULAR SCAFFOLD; INTERSTRAND-STACKING; CATIONIC PORPHYRINS; ARRAYS; BASE; OLIGONUCLEOTIDES; NANOTECHNOLOGY; SCALE; FLUORESCENCE;
D O I
10.1002/anie.200805657
中图分类号
O6 [化学];
学科分类号
0703 ;
摘要
(Chemical Equation Presented) Zip it up: Attachment of porphyrins onto complementary DNA strands leads to zipper-porphyrin arrays and, in the presence of eleven modifications, an increase in the melting temperature of the duplex. Mixed zinc and free-base porphyrin arrays undergo energy transfer from the zinc porphyrin to the free-base porphyrin in the annealed duplex but not in the denatured form (see scheme), giving access to reversible formation of potential photonic wires. © 2009 Wiley-VCH Verlag GmbH & Co. KGaA.
引用
收藏
页码:1974 / 1977
页数:4
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