An Expedient Access to γ-Ketophosphine Chalcogenides via the Chemo- and Regioselective Addition of Secondary Phosphine Chalcogenides to β,γ-Ethylenic Ketones

被引：3

作者：

Artem'ev, Alexander V. ^{[1
]}

Malysheva, Svetlana F. ^{[1
]}

Belogorlova, Nataliya A. ^{[1
]}

Protzuk, Nadezhda I. ^{[1
]}

Albanov, Alexander I. ^{[1
]}

Bagryanskaya, Irina Yu. ^{[2
,3
]}

Schmidt, Elena Yu. ^{[1
]}

Gusarova, Nina K. ^{[1
]}

Trofimov, Boris A. ^{[1
]}

机构：

[1] Russian Acad Sci, AE Favorsky Irkutsk Inst Chem, Siberian Branch, Irkutsk 664033, Russia

[2] Russian Acad Sci, NN Vorozhtsov Novosibirsk Inst Organ Chem, Siberian Branch, Novosibirsk 630090, Russia

[3] Novosibirsk State Univ, Novosibirsk 630090, Russia

来源：

HETEROATOM CHEMISTRY | 2015年 / 26卷 / 06期

关键词：

ONE-POT SYNTHESIS; STEREOSELECTIVE ALPHA-VINYLATION; HYDROXYPHOSPHINE OXIDES; BETA-KETOPHOSPHONATES; DIMETHYLPHOSPHINE OXIDE; CATALYZED ADDITION; KEY STEP; ARYLACETYLENES; PHOSPHONATES; SULFIDES;

D O I：

10.1002/hc.21281

中图分类号：

O6 [化学];

学科分类号：

0703 ;

摘要：

gamma-Ketophosphine chalcogenides, precursors for plethora of novel functionalized phosphine chalcogenides and phosphines, are synthesized by chemo- and regioselective addition of secondary phosphine chalcogenides to beta,gamma-ethylenic ketones under catalyst-and solvent-free conditions (80-100 degrees C, 8-70 h) in excellent yields. The straightforward superbase-catalyzed synthesis of starting beta,gamma-ethylenic ketones from ketones and acetylenes insures the expedient access to the target gamma-ketophosphine chalcogenides. (C) 2015 Wiley Periodicals, Inc.

引用

页码：455 / 462

页数：8

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