Red potato extract protects from D-galactosamine-induced liver injury in rats

被引:12
作者
Han, Kyu-Ho
Hashimoto, Naoto
Hashimoto, Makoto
Noda, Takahiro
Shimada, Ken-ichiro
Lee, Chi-Ho
Sekikawa, Mitsuo
Fukushima, Michihiro [1 ]
机构
[1] Obihiro Univ Agr & Vet Med, Dept Agr & Life Sci, Obihiro, Hokkaido 0808555, Japan
[2] Natl Agr Res Ctr Hokkaido Reg, Dept Upland Agr, Memuro, Hokkaido 0820071, Japan
[3] Konkuk Univ, Dept Food Sci & Biotechnol Anim Resources, Seoul 143701, South Korea
基金
日本学术振兴会;
关键词
colored potato; anthocyanin; D-galactosamine; hepatotoxicity; rat;
D O I
10.1271/bbb.60097
中图分类号
Q5 [生物化学]; Q7 [分子生物学];
学科分类号
071010 ; 081704 ;
摘要
The protective effects of red potato extract (RPE) as to liver damage were determined in D-galactosamine (GaIN)-intoxicated rats. Increases in serum aspartate aminotransferase, alanine aminotransferase, and lactate dehydrogenase activities, all of which were induced by GaIN injection, decreased in RPE administered rats, suggesting that RPE acts as a functional food showing anti-hepatotoxicity.
引用
收藏
页码:2285 / 2288
页数:4
相关论文
共 29 条
  • [1] Antioxidants in potato
    Brown, CR
    [J]. AMERICAN JOURNAL OF POTATO RESEARCH, 2005, 82 (02) : 163 - 172
  • [2] A FLUOROMETRIC ASSAY FOR GLUTATHIONE
    COHN, VH
    LYLE, J
    [J]. ANALYTICAL BIOCHEMISTRY, 1966, 14 (03) : 434 - &
  • [3] Suppressive effect of corn bran hemicellulose on liver injury induced by D-galactosamine in rats
    Daizo, A
    Egashira, Y
    Sanada, H
    [J]. NUTRITION, 2005, 21 (10) : 1044 - 1051
  • [4] Anthocyanins from pigmented potato (Solanum tuberosum L.) varieties
    Eichhorn, S
    Winterhalter, P
    [J]. FOOD RESEARCH INTERNATIONAL, 2005, 38 (8-9) : 943 - 948
  • [5] Giusti M. M., 2001, Curr. Protoc. FoodAnal. Chem, P1, DOI [10.1002/0471142913.faf0102-00, DOI 10.1002/0471142913.FAF0102S00]
  • [6] Free-radical scavenging action of medicinal herbs from Ghana Thonningia sanguinea on experimentally-induced liver injuries
    Gyamfi, MA
    Yonamine, M
    Aniya, Y
    [J]. GENERAL PHARMACOLOGY, 1999, 32 (06): : 661 - 667
  • [7] Hepatoprotective effects of purple potato extract against D-galactosamine-induced liver injury in rats
    Han, Kyu-Ho
    Hashimoto, Naoto
    Shimada, Ken-ichiro
    Sekikawa, Masuo
    Noda, Takahiro
    Yamauchi, Hiroaki
    Hashimoto, Makoto
    Chiji, Hideyuki
    Topping, David L.
    Fukushima, Michihiro
    [J]. BIOSCIENCE BIOTECHNOLOGY AND BIOCHEMISTRY, 2006, 70 (06) : 1432 - 1437
  • [8] SPECTRAL METHODS OF CHARACTERIZING ANTHOCYANINS
    HARBORNE, JB
    [J]. BIOCHEMICAL JOURNAL, 1958, 70 : 22 - 28
  • [9] Preventive effects of dietary boysenberry anthocyanins on galactosamine-induced liver injury in rats
    Igarashi, K
    Sugimoto, E
    Hatakeyama, A
    Molyneux, J
    Kubomura, K
    [J]. BIOFACTORS, 2004, 21 (1-4) : 259 - 261
  • [10] The determination of flavonoid contents in mulberry and their scavenging effects on superoxide radicals
    Jia, Z
    Tang, MC
    Wu, JM
    [J]. FOOD CHEMISTRY, 1999, 64 (04) : 555 - 559