Trabecular Bone Score: Where are we now?

被引：38

作者：

Bousson, Valerie ^{[1
,2
]}

Bergot, Catherine ^{[2
]}

Sutter, Bruno ^{[3
]}

Thomas, Thierry ^{[4
]}

Bendavid, Sauveur ^{[5
]}

Benhamou, Claude-Laurent ^{[6
]}

Blain, Hubert ^{[7
]}

Brazier, Michel ^{[8
]}

Breuil, Veronique ^{[9
]}

Briot, Karine ^{[10
]}

Chapurlat, Roland ^{[11
]}

Chapuis, Laure ^{[12
]}

Solar, Martine Cohen ^{[13
]}

Fardellone, Patrice ^{[14
]}

Feron, Jean-Marc ^{[15
]}

Gauvain, Jean-Bernard ^{[16
]}

Laroche, Michel ^{[17
]}

Legrand, Erick ^{[18
]}

Lespessailles, Eric ^{[6
]}

Linglart, Agnes ^{[19
]}

Marcelli, Christian ^{[20
]}

Roux, Christian ^{[10
]}

Souberbielle, Jean-Claude ^{[21
]}

Tremollieres, Florence ^{[22
]}

Weryha, Georges ^{[23
]}

Cortet, Bernard ^{[24
]}

机构：

[1] Univ Paris 07, Hop Lariboisiere, AP HP, Radiol Osteoarticulaire,Sorbonne Paris Cite, F-75010 Paris, France

[2] CNRS, B20A, UMR 7052, F-75010 Paris, France

[3] Grp HOPALE, Inst Calot, Unite Med Nucl, F-62608 Berck Sur Mer, France

[4] CHU St Etienne, Serv Rhumatol, Inserm U1059, F-42055 St Etienne 2, France

[5] Med Gen, F-75014 Paris, France

[6] Univ Orleans, EA4708, I3MTO, F-45100 Orleans, France

[7] CHU Montpellier, Ctr Antonin Balmes, Pole Geriatr, F-34295 Montpellier, France

[8] CHU Amiens, Lab Biol Endocrinienne & Osteoarticulaire, F-80054 Amiens, France

[9] Univ Nice Sophia Antipolis, CHU Nice 1, Serv Rhumatol, F-06200 Nice, France

[10] Univ Paris 05, Hop Cochin, Serv Rhumatol, F-75014 Paris, France

[11] Hop Edouard Herriot, Serv Rhumatol, Inserm U403, F-69003 Lyon, France

[12] Serv Rhumatol, F-35500 Vitre, France

[13] Univ Paris 07, Hop Lariboisiere, Inserm U606, F-75010 Paris, France

[14] CHU Amiens, Serv Rhumatol, Inserm ERI 12, F-80054 Amiens 2, France

[15] Hop St Antoine, Serv Chirurg Orthoped, F-75012 Paris, France

[16] CHR, Ctr Med Geriatr, F-45032 Orleans, France

[17] CHU Purpan, Ctr Rhumatol, F-31059 Toulouse, France

[18] CHU Angers, Serv Rhumatol, F-49933 Angers 09, France

[19] Serv Endocrinol Diabetol Pediat, F-94270 Le Kremlin Bicetre, France

[20] Hop Cote de Nacre, Serv Rhumatol, F-14033 Caen 09, France

[21] Hop Necker Enfants Malad, Lab Explorat Fonct, Inserm U845, F-75015 Paris, France

[22] Hop Paule de Viguier, Ctr Menopause, F-31000 Toulouse, France

[23] CHU Nancy, Serv Endocrinol, F-54511 Vandoeuvre Les Nancy, France

[24] Hop Roger Salengro, Serv Rhumatol, F-59037 Lille, France

来源：

JOINT BONE SPINE | 2015年 / 82卷 / 05期

关键词：

Osteoporosis; Fragility fracture; Densitometry; Bone mineral density; Trabecular Bone Score; MINERAL DENSITY; LUMBAR SPINE; PRIMARY HYPERPARATHYROIDISM; OSTEOPOROTIC FRACTURES; POSTMENOPAUSAL WOMEN; VERTEBRAL FRACTURES; CAUCASIAN WOMEN; WHITE WOMEN; TBS; MICROARCHITECTURE;

D O I：

10.1016/j.jbspin.2015.02.005

中图分类号：

R5 [内科学];

学科分类号：

1002 ; 100201 ;

摘要：

The Trabecular Bone Score is a rather new index obtained at the lumbar spine at the same time as a real bone mineral density. It was developed to reflect bone microarchitecture. It was proposed to be easily used in everyday practice as a surrogate of bone strength. Our aim was to review 1. technical points such as correlations between Trabecular Bone Score and bone microarchitectural parameters, Trabecular Bone Score and bone strength, the effects of dual-energy X-ray absorptiometry image spatial resolution, age, macroarchitecture, body mass index, and osteoarthritis, on Trabecular Bone Score, and 2. evidences to use Trabecular Bone Score for separating individuals with fragility fractures from controls, predicting fragility fractures, and for longitudinally monitoring changes related to treatments. Correlations between Trabecular Bone Score and bone microarchitectural parameters vary widely across bone sites, microarchitectural parameters, and study designs. In vivo, the Trabecular Bone Score explains little of the variance in trabecular microarchitectural parameters. We emphasize that it is a texture parameter. The Trabecular Bone Score is reduced in patients with fragility fracture. Several retrospective and prospective studies have shown its discriminative ability regarding the fracture risk. When combining the areal Bone mineral Density and Trabecular Bone Score, the Trabecular Bone Score remains a predictor of fracture but not the areal Bone Mineral Density. However in prospective studies, the best predictor of fracture remains hip areal bone mineral density. Due to the lack of evidence, we recommend not to use Trabecular Bone Score for following patients treated by anti-osteoporotic drugs. (C) 2015 Societe francaise de rhumatologie. Published by Elsevier Masson SAS. All rights reserved.

引用

页码：320 / 325

页数：6

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