Synthesis and antibacterial activity of 3-cyano-2-(1H)-pyridone derivatives

被引：0
|
作者：
Desai, MD [1 ]
Desai, KK [1 ]
机构：
[1] S Gujarat Univ, Dept Chem, Surat 395007, India
来源：
ASIAN JOURNAL OF CHEMISTRY | 2002年 / 14卷 / 3-4期
关键词：
synthesis; antibacterial; 3-cyano-2-(1H) pyridone derivatives;
D O I：
暂无
中图分类号：
O6 [化学];
学科分类号：
0703 ;
摘要：
Several new 3-cyano-4-substituted aryl-6-[2'-hydroxy-4'-(p-trifluromethyl/nitro-phenoxy)-phen-1'-yl]-2-(1H)-pyridone (II) have been prepared by reaction of 1-[2'-hydroxy-4'-(p-trifluoromethyl/nitro phenoxy)-phen-1'-yl-3-substituted aryl-2-propene-1-ones (I) with ethyl cyanoacetate and ammonium acetate in ethanol. Few of these compounds are characterized by IR and NMR spectra: All these synthesized 3-cyano-2-pyridones have been screened against a few microorganisms for antibacterial activity.
引用
收藏
页码：1383 / 1386
页数：4
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