Optoelectrical microfluidics as a promising tool in biology

被引:27
|
作者
Mishra, Avanish [1 ]
Kwon, Jae-Sung [1 ]
Thakur, Raviraj [1 ]
Wereley, Steve [1 ]
机构
[1] Purdue Univ, Sch Mech Engn, Birck Nanotechnol Ctr, W Lafayette, IN 47907 USA
关键词
electrokinetics; optofluidics; cell manipulation; optical tweezers; microfluidics; patterning; CELL MANIPULATION; RARE CELLS; TWEEZERS; MICROPARTICLES; PARTICLE; CHIP; ELECTROPORATION; FLOW;
D O I
10.1016/j.tibtech.2014.06.002
中图分类号
Q81 [生物工程学(生物技术)]; Q93 [微生物学];
学科分类号
071005 ; 0836 ; 090102 ; 100705 ;
摘要
Noncontact robotic particle grippers with trapping, manipulation, and release functions are highly desired in cell biology and microfluidics. Optoelectric techniques combine optical and electrokinetic effects to create thousands of such individually addressable traps. By projecting reconfigurable light patterns, these techniques can concentrate molecules, as well as manipulate, sort, and electroporate cells in a programmable manner. We describe the underlying physical mechanisms and discuss applications in biology and future prospects of these devices.
引用
收藏
页码:415 / 422
页数:8
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