Direct formation of mesoporous upconverting core-shell nanoparticles for bioimaging of living cells

被引：24

作者：

Sun, Lining ^{[1
]}

Liu, Tao ^{[1
]}

Qiu, Yannan ^{[1
]}

Liu, Jinliang ^{[1
]}

Shi, Liyi ^{[1
]}

Wolfbeis, Otto S. ^{[2
]}

机构：

[1] Shanghai Univ, Res Ctr Nano Sci & Technol, Shanghai 200444, Peoples R China

[2] Univ Regensburg, Inst Analyt Chem Chemo & Biosensors, D-93040 Regensburg, Germany

来源：

MICROCHIMICA ACTA | 2014年 / 181卷 / 7-8期

基金：

中国国家自然科学基金;

关键词：

Upconversion nanophosphor; Mesoporous silica; Core-shell; Luminescence imaging; Biocompatible nanoparticles; UP-CONVERSION NANOPARTICLES; SILICA SHELL; LUMINESCENT; UNIFORM; NANOCRYSTALS; NANOSYSTEM;

D O I：

10.1007/s00604-013-1073-9

中图分类号：

O65 [分析化学];

学科分类号：

070302 ; 081704 ;

摘要：

We have developed a one-step method for the synthesis of mesoporous upconverting nanoparticles (MUCNs) of the type NaYF4:Yb,Er@mSiO(2) in ammoniacal ethanol/water solution. The mesoporous silica is directly encapsulating the hydrophobic upconversion nanoparticles (UCNs) due to the presence of the template CTAB. Intense green emission (between 520 and 560 nm) and weaker red emission (between 630 and 670 nm) is observed upon 980-nm laser excitation. The MUCNs display low cytotoxicity (as revealed by an MTT test) and were successfully applied to label and image human nasopharyngeal epidermal carcinoma (KB) cells.

引用

页码：775 / 781

页数：7

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