Postintervention duration of anticoagulation in venous surgery

被引:3
|
作者
Ten Cate-Hoek, A. J. [1 ,2 ,3 ]
Prins, M. H.
Wittens, C. H. A. [1 ,2 ,3 ,4 ,5 ]
Cate, H. ten [1 ,2 ,3 ]
机构
[1] Cardiovasc Res Inst Maastricht CARIM, Dept Internal Med, Maastricht, Netherlands
[2] Cardiovasc Res Inst Maastricht CARIM, Dept Clin Epidemiol, Maastricht, Netherlands
[3] Maastricht Univ, Sch Publ Hlth & Primary Care Caphrie, Maastricht, Netherlands
[4] Univ Hosp, Dept Vasc Surg, Maastricht, Netherlands
[5] Univ Klinikum Aachen, Dept Vasc Surg, Aachen, Germany
关键词
DEEP-VEIN-THROMBOSIS; D-DIMER; POSTTHROMBOTIC SYNDROME; RISK-FACTORS; LONG-TERM; COMPRESSION STOCKINGS; CONTROLLED-TRIAL; THROMBOEMBOLISM; RECURRENCE; OBSTRUCTION;
D O I
10.1177/0268355513476415
中图分类号
R61 [外科手术学];
学科分类号
摘要
For a substantial proportion of patients with deep venous thrombosis (DVT), current treatment strategies are suboptimal and new treatment options are needed. Especially for the group of patients who are at the highest risk for post-thrombotic syndrome, new treatment modalities such as catheter-directed thrombolysis and additional stenting are being investigated. With current clinical studies addressing new technical options, the medical management of patients following these interventions deserves attention. The duration of anticoagulant treatment following surgical or radiological interventions for DVT seems not to be influenced by the presence of a venous stent. According to recent ACCP 2012 guidelines the anticoagulant management in patients who have had any method of thrombus removal performed, the same intensity and duration of anticoagulant therapy as in comparable patients who do not undergo thrombosis removal is recommended (Grade 1B). In the acute phase of thrombosis, irrespective of the technique and whether or not stenting is applied, immediate anticoagulation following the procedure is pertinent to reduce the risk of recurrent thrombosis and thrombus propagation. The long-term treatment duration after venous interventions therefore may be tailored based on common risk factors for recurrent thrombosis and the individual risk for bleeding. Selected thrombophilia factors, d-dimer assessment and residual venous thrombosis provide markers for recurrent DVT. Currently, vitamin K antagonists) provide the main anticoagulants for (prolonged) anticoagulation, while the new oral anticoagulants emerge as promising alternatives. In case prolonged anticoagulation after unprovoked DVT is not indicated, cardiovascular risk management is warranted because of an increased rate of arterial thrombotic events after DVT; aspirin may be indicated as secondary prevention against recurrent thrombosis (while providing primary prevention against arterial thrombosis).
引用
收藏
页码:105 / 111
页数:7
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